Pesticides driven from Plants, animals, and microbes such as (bacteria fungi, viruses, algae, nematodes and protozoa are replacing traditional chemical pesticides throughout the world. Bio pesticides reduce environmental risks and are target specific. Bio pesticide promotes sustainable agriculture development by reducing the environmental pollution. Various products have been registered and released, that play important role in the agro-market. Regulation of many insect populations in nature happen by Baculoviruses (entomopathogenic viruses). The pesticide based on baculovirus particles has been formed to control pest and their use is beneficial to reduce the risk of synthetic chemical insecticides. The present status and increase use of baculovirus based bio pesticides as replacement of chemical pesticides, its role in integrated pest management, have been discussed in this review.