Anal ulceration associated with Nicorandil: case series and review of the literature

Toquero, Lawrence; Briggs, Christopher; Bassuini, M. M. A.; Rochester, J.

doi:10.1111/j.1463-1318.2006.00972.x

Cited by 44 publications

(30 citation statements)

References 9 publications

(21 reference statements)

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“…Despite these promising reports on the use of topical potassium channel openers for anal fissure treatment, there have been a number of case reports of anal ulcers associated with the use of nicorandil, a common oral potassium channel opener used for angina [163][164][165][166]. The mechanism of action is unclear.…”

Section: Potassium Channel Openersmentioning

confidence: 87%

A review of chronic anal fissure management

Collins

Lund

2007

Tech Coloproctol

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Anal fissure management has rapidly progressed in the last 15 years as our understanding of fissure pathophysiology has developed. All methods of treatment aim to reduce the anal sphincter spasm associated with chronic anal fissures. Surgical techniques have been used for over 100 years with success. Lateral internal sphincterotomy remains the surgical treatment of choice for many practitioners. Postoperative impairment of continence remains controversial. Recently, less invasive methods of treatment have been explored. Topical nitrates, calcium channel blockers and botulinum toxin are established treatments. These and other non-surgical treatments are described in this review. Various guidelines and treatment algorithms for anal fissure are also discussed.

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Section: Potassium Channel Openersmentioning

confidence: 87%

A review of chronic anal fissure management

Collins

Lund

2007

Tech Coloproctol

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“…[1][2][3][4][5][6][7][8][9][10][11][12] After withdrawal of nicorandil, ulcer healing may take place in as little as two weeks. In most cases it takes at least 12 weeks and in some cases up to six months.…”

Section: Discussionmentioning

confidence: 99%

Anal ulceration induced by nicorandil

Akbar

Maw

Bhowmick

2007

BMJ

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“…Ursache ist in diesem Fall die medikamentöse Wirkung per anum eingeführ-ter Substanzen (Zäpfchen, Schaum oder Einläufe [3].…”

Section: Medikamentös Bedingtunclassified

Proktitis aus Sicht der Proktologie*

et al. 2010

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Proktitis ist eine Entzündung des Rektums und geht mit völlig unspezifischen Symptomen wie transanalen Blutungen, häufigem Stuhldrang (Tenesmen), Schleimbeimischungen, Schmerzen usw. einher. Die Proktitis kann unterschiedliche Ursachen haben. In diesem Beitrag werden die infektiösen Ursachen wie die sexuell übertragbaren Krankheiten oder Infektionen (STD oder STI, Herpes, Chlamydien, Gonorrhö usw.) und die spezifischen chronisch-entzünd-lichen Darmerkrankungen (CED, Morbus Crohn, Colitis ulcerosa), die auch mit einer Proktitis einhergehen können, nicht abgehandelt. Im Folgenden werden zunächst die Symptome, Befunde und Differenzialdiagnostik besprochen. Anschließend werden die häufigsten Ursachen für "proktologische" Proktitiden in aufsteigender Reihenfolge ihrer Häu-figkeit in der Praxis abgehandelt (externe Agenzien eher selten, radiogen bedingte Proktitis am häufigsten). Proktitis aus Sicht der Proktologie Übersichtsarbeit Abb. 1 7 Rektales Ulkus nach Abusus von Suppositorien mit Paracetamol und Codein 273 coloproctology 5 · 2010 |

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Anal ulceration associated with Nicorandil: case series and review of the literature

Cited by 44 publications

References 9 publications

A review of chronic anal fissure management

A review of chronic anal fissure management

Anal ulceration induced by nicorandil

Proktitis aus Sicht der Proktologie*

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