Anal polyp caused by Schistosoma mansoni

Raso, Pedro; Sander, Eliane Mansur; Raso, Leonardo Arruda Moraes; Filho, José de Souza Andrade

doi:10.1590/0037-8682-1681-2013

Cited by 5 publications

(3 citation statements)

References 11 publications

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“…It is unusual for schistosomiasis to have evidence of infection after the fibrotic phase has occurred. Rarely, worms may be found alive, mating, or dead within the inflammatory reaction 5 ; however, this is the first case to describe colonic polyps with male and female worms and associated eggs on histology. It is remarkable to have an active infection years after living in a nonendemic region.…”

Section: Case Reportmentioning

confidence: 82%

Eggs, Worms, or Both? Chronic Active Schistosomiasis Presenting as Cirrhosis and Colonic Polyps

Karim

Adeyemo

Bilal³

et al. 2022

ACG Case Rep J

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Section: Case Reportmentioning

confidence: 82%

Eggs, Worms, or Both? Chronic Active Schistosomiasis Presenting as Cirrhosis and Colonic Polyps

Karim

Adeyemo

Bilal³

et al. 2022

ACG Case Rep J

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“…The primary presenting symptoms of intestinal schistosomiasis are usually tenesmus and the rectal passage of blood and mucous and bloody diarrhea [144]. Egg deposition and granuloma formation eventually lead to acute then chronic schistosomal colitis and are commonly associated with polyp formation [145][146][147][148]. The preferential site of schistosomal polyps is the rectum, followed by the sigmoid colon [149].…”

Section: Intestinal Schistosomiasismentioning

confidence: 99%

Does Schistosoma Mansoni Facilitate Carcinogenesis?

Bülow

Lichtenberger

Grevelding

et al. 2021

Cells

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Schistosomiasis is one of the most prominent parasite-induced infectious diseases, causing tremendous medical and socioeconomic problems. Current studies have reported on the spread of endemic regions and the fear of development of resistance against praziquantel, the only effective drug available. Among the Schistosoma species, only S. haematobium is classified as a Group 1 carcinogen (definitely cancerogenic to humans), causing squamous cell carcinoma of the bladder, whereas infection with S. mansoni is included in Group 3 of carcinogenic hazards to humans by the International Agency for Research on Cancer (IARC), indicating insufficient evidence to determine its carcinogenicity. Nevertheless, although S. mansoni has not been discussed as an organic carcinogen, the multiplicity of case reports, together with recent data from animal models and cell culture experiments, suggests that this parasite can predispose patients to or promote hepatic and colorectal cancer. In this review, we discuss the current data, with a focus on new developments regarding the association of S. mansoni infection with human cancer and the recently discovered biomolecular mechanisms by which S. mansoni may predispose patients to cancer development and carcinogenesis.

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“…In more than 70 countries the infection is endemic with an estimated 660 million infections are concentrated in Africa, which accounts for 85% of the global at-risk estimated [ 1 – 3 ] Schistosoma can affect any site in the digestive tract, but the preferred site is the rectum while the sigmoid is rarely effected, and on occasion, it is found in the other parts of the large and small intestines. The polyp consists of a combination of a vascular neoformation and an inflammatory reaction to parasite eggs; worm can be found either dead or alive inside the polyp tissue [ 4 ] S. mansoni may be associated with the sexually transmitted disease as its eggs have been isolated from the condyloma acuminatum of patients with positive tests for human papillomavirus (HPV) in addition to human immunodeficiency virus (HIV) patients [ 5 , 6 ] .…”

Section: Introductionmentioning

confidence: 99%

Colonic Polyps an Unusual Manifestation of Schistosomiasis

et al. 2020

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Patient: Male, 24-year-old Final Diagnosis: Large rectal polyps secondary to Schistosoma infection • Unusual colonic polyp caused by Schistoma infection Symptoms: Abdominal pain • bleeding per rectum Medication: During the procedure: Xylocaine local gel • Midazolam inj • Fentanyl inj; For the disease: Praziquantel tab Clinical Procedure: Colonoscopy with endoscopic submucosal resection (EMR) • endoscopic submucosal resection (EMR) Specialty: Gastroenterology and Hepatology • Endoscopy Objective: Report of misleading rare disease to avoid an unnecessary invasive intervention Background: Although reports of bilharizial colonic polyps are very rare in the literature, we report a case of a large rectal polyp as a manifestation of chronic intestinal bilharzia. A high index of suspicion in an endemic area is the key factor to avoid unnecessary medical interventions. Case Report: We report a case of a 24-year-old male patient who was married, born in Taiz North Yemen, and worked as a military soldier. He presented to our clinic with a complaint concerning intermittent lower abdominal pain and several months of rectal bleeding. A colonoscopy was performed at the Endoscopy Unit of King Khalid Hospital, Najran, Saudi Arabia on September 23, 2019 and results showed 2 large rectal polyps, (measuring 4×3 and 2×3 cm), located 10 cm from the anal verge, having wide bases and irregular surfaces that mimicked dysplastic polyps. Both polyps became elevated after a normal saline/methylene blue injection. An endoscopic mucosal resection was successfully performed with no immediate complications. The histopathology showed benign polyps due to Schistosoma -induced colonic infection. Conclusions: It is very difficult and challenging to differentiate Schistosoma -induced colonic polyps from other colonic polyps even with an endoscopic evaluation; thus, a high index of clinical suspicion is required mainly in an endemic area, which may prevent the physician from ordering unnecessary interventions and thus avoid severe complications.

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Anal polyp caused by Schistosoma mansoni

Cited by 5 publications

References 11 publications

Eggs, Worms, or Both? Chronic Active Schistosomiasis Presenting as Cirrhosis and Colonic Polyps

Eggs, Worms, or Both? Chronic Active Schistosomiasis Presenting as Cirrhosis and Colonic Polyps

Does Schistosoma Mansoni Facilitate Carcinogenesis?

Colonic Polyps an Unusual Manifestation of Schistosomiasis

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