Anaemia and congestive heart failure early post-renal transplantation

Borrows, Richard; Loucaidou, Marina; Chusney, Gary; Borrows, Sarah; Tromp, Jen Van; Cairns, Tom; Griffith, Megan; Hakim, Nadey; McLean, Adam; Palmer, Andrew J.; Papalois, Vassilios; Taube, David

doi:10.1093/ndt/gfm815

Cited by 19 publications

(14 citation statements)

References 33 publications

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“…The predictors of early HF following kidney transplant have not been well studied. In a recent study of 132 kidney transplant recipients, early HF was common and was associated with post-transplant anemia, allograft dysfunction, duration of dialysis prior to transplant, and degree of pretransplant LVH 22. Of note, in our study sample the relative rise in HF risk early after transplant was smaller with living compared to deceased donor transplantation across BMI strata, possibly reflecting superior early graft function in this cohort.…”

Section: Discussionmentioning

confidence: 48%

The impact of kidney transplantation on heart failure risk varies with candidate body mass index

Lentine

Xiao

Brennan

et al. 2009

American Heart Journal

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Section: Discussionmentioning

confidence: 48%

The impact of kidney transplantation on heart failure risk varies with candidate body mass index

Lentine

Xiao

Brennan

et al. 2009

American Heart Journal

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“…It is possible that the dominant influence of some factors prevented the detection of factors that are of less prognostic importance. The literature showed very confusing data on the role of various factors in poor outcomes in renal patients [7][8][9][10][11][12][13][29][30][31][32][33][34][35]. These discrepancies may be related to differences in population characteristics, sampling size, observation time, method of analysis and the impact of confounding covariates on the outcome of multivariate analysis.…”

Section: Discussionmentioning

confidence: 99%

Predictors for cardiovascular morbidity and overall mortality in Tunisian ESRD patients: A six year prospective study

Fellah

Hammami

Feki

et al. 2009

Clinical Biochemistry

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“…Prior studies have reported anatomic and functional abnormalities in kidney transplant recipients,10)11) but the effects of kidney transplant on LV rotation, twist and torsion has never been investigated. Therefore, we employed velocity vector imaging to assess LV rotation, twist and torsion pre and post kidney transplant in end stage renal disease patients without myocardial infarction.…”

Section: Introductionmentioning

confidence: 99%

Left Ventricular Torsion Changes Post Kidney Transplantation

Deng

Pandit

Heilman

et al. 2013

J Cardiovasc Ultrasound

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BackgroundTo quantify changes of left ventricular (LV) torsion in patients' pre and post kidney transplantation.MethodsA prospective study was conducted on 48 patients who received kidney transplantation for end stage renal disease and without myocardial infarction. The rotation, twist and torsion of LV were studied pre and post kidney transplantation (6 months post transplantation) using velocity vector imaging by echocardiography. The data is expressed as mean ± standard deviation and compared by paired t-test at the p < 0.05 significance level.ResultsSix months post kidney transplantation, left ventricular ejection fraction (from 40.33 ± 11.42 to 61.00 ± 13.68%), ratio of mitral early and late diastolic filling velocity (from 1.04 ± 0.57 to 1.21 ± 0.52), rotation of basal LV (from 4.48 ± 2.66 to 5.65 ± 2.64 degree), rotation of apical LV (from 4.27 ± 3.08 to 5.50 ± 4.25 degree), LV twist (8.75 ± 4.45 to 11.14 ± 5.25 degree) and torsion (from 1.06 ± 0.54 to 1.33 ± 0.61 degree/cm) were increased significantly (p < 0.05). Interventricular septum thickness (from 11.67 ± 2.39 to 9.67 ± 0.48 mm), left ventricular mass index (from 104.00 ± 16.47 to 95.50 ± 21.44 g/m2), systolic blood pressure (from 143.50 ± 34.99 to 121.50 ± 7.09 mmHg), serum blood urea nitrogen (from 42.40 ± 7.98 to 30.43 ± 13.85 mg/dL) and creatinine (from 4.53 ± 1.96 to 2.73 ± 2.57 mg/dL) were decreased significantly (p < 0.05).ConclusionKidney transplantation in end stage renal disease without myocardial infarction results in improvement in left ventricular structure, function and myocardial mechanics as detected by echocardiography and velocity vector imaging. Velocity vector imaging provided valuable information for detection and follow-up of cardiac abnormalities in patients with end stage renal disease.

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Anaemia and congestive heart failure early post-renal transplantation

Abstract: Modification of risk factors may improve anaemia management post transplantation. Reducing the prevalence of anaemia may in turn reduce the incidence of CHF-these observations support the need for clinical trials to determine how anaemia management may impact CHF incidence.

Cited by 19 publications

References 33 publications

The impact of kidney transplantation on heart failure risk varies with candidate body mass index

The impact of kidney transplantation on heart failure risk varies with candidate body mass index

Predictors for cardiovascular morbidity and overall mortality in Tunisian ESRD patients: A six year prospective study

Left Ventricular Torsion Changes Post Kidney Transplantation

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