“…In the past several decades, some marine-cultured animals including Lates calcarifer, Sparus aurata, Dicentrarchus labrax, Litopenaeus vannamei, Marsupenaeus japonicas, and Crassostrea gigas sufered serious production losses due to infection by V. alginolyticus [2][3][4][5][6][7]. It has been reported that V. alginolyticus also infected humans and caused gastroenteritis, wound infections, and septicemia and even amputations and death [8]. Due to the harmful efect caused by V. alginolyticus, farmers had to combat the disease with some treatment ways, such as antibiotics, green water technique, topical disinfectants, medicinal plants, bacteriophage, probiotics, and vaccines [9].…”