An Overview on the Effects of Sodium Benzoate as a Preservative in Food Products

Shahmohammadi, Mojtaba; Javadi, Maryam; Nassiri‐Asl, Marjan

doi:10.17795/bhs-35084

Cited by 53 publications

(35 citation statements)

References 28 publications

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“…22192/ijarbs.2018.05.06.011 Sodium benzoate It is the sodium salt of the nonessential aminoacid glutamic acid, sodium benzoate it has number E211. IT is the sodium salt of benzene carboxylic acid (benzoic acid) with the chemical formula C 7 H 5 NaO 2 (Mpountoukas et al, 2008;Shahmohammadi et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Alterations in Oxidative Stress and Antioxidantin Albino rats Treated with Individual and Combined Various Food Additives

Moeen¹,

Elhalwagy²,

Ayaz³

2018

Int. J. Adv. Res. Biol. Sci.

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Aim: food additives are substances of natural or synthetic origin, which are added to foods to serve a certain technological or sensory function. this work was aimed to investigate the effects of individual and combined treatment of artificial food additives on oxidative stress, antioxidant parameters in male juvenile albino rats. Exparimental Design:Thirty youngmale albino rats weighing around 90-110 gm. were divided into six groups (5 /cage); Group I: (Control untreated group), Group II: treated with MSG (300mg/kg), Group III: treated with Sodium benzoate (5mg /kg), Group IV: treat with Carmoisine (4mg/kg), Group V: treated with EDTA (2.5mg/kg), Group VI: treated with mixture of MSG (300/kg), Carmosine (4mg/kg), Sodium benzoate (5mg/kg) and EDTA (2.5 mg/ kg) simultaneously. All the treatments for 28 days. Results:The obtained results revealed elevation in oxidative stress markers malondialdehyde MDA and protein carbonyl PC in individually treated MSG and sodium benzoate and remarkable in mixture group. Significant reduction in catalase, total antioxidant capacity, and glutathione content were recorded in individually treated groups and pronounced in mixture group.Concolusion: food additives affect adversely on oxidative stress and antioxidant markers that may cause adverse health effects. It is advisable to limit the uses of commodities containing these additives.

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Section: Introductionmentioning

confidence: 99%

Alterations in Oxidative Stress and Antioxidantin Albino rats Treated with Individual and Combined Various Food Additives

Moeen¹,

Elhalwagy²,

Ayaz³

2018

Int. J. Adv. Res. Biol. Sci.

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“…Sodium benzoate (SB) is widely used in food products, especially as complement food/seasoning such as: chili sauce, ketchup, tomato sauce, carbonated drinks, etc. (Sumantri et al, 2015) and is classified as generally recognized as safe (GRAS) by FDA (Shahmohammadi et al, 2016). The allowable limit of the SB application as preservative in the food products may differ from one country another.…”

Section: Introductionmentioning

confidence: 99%

Inhibitory effect of Sodium Benzoate as Preservative Material in the Biogas Production in a Batch Anaerobic Digestion Process

Sumantri¹,

Buchori²,

Anggoro³

2020

J. Ecol. Eng.

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Sodium benzoate has been used a food preservative worldwide. The effect of sodium benzoate as a preservative in the wastewater treatment was examined from the biogas formation viewpoint. The research was conducted in batch mode reactor systems employing various ratios of activated sludge and solution of sodium benzoate volume. The MLSS of activated sludge used was 12 g/L, while the volume ratios of activated sludge and sodium benzoate ranged from 0 to 100%. The concentrations of sodium benzoate used were 50, 100, and 200 mg/L. The biogas samples were measured every two days for 60 days. The results showed that the volume ratio of activated sludge and sodium benzoate of 60% and 40% was a turning point where the existence of sodium benzoate influenced the formation of biogas. There were significant reductions of biogas formation from 200.6 mL to 66.6 mL, 159.8 mL to 66.0 mL and 130.2 mL to 54.0 mL for the initial SB concentrations of 50, 100, and 200 mg/L. The kinetic parameters of the Modified Gompertz equation exhibited the greatest degree of confidence equal to 95%.

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“…Although sodium benzoate (SB) is accepted as a safe substance, but short-term exposure can cause irritation of eyes, skin and respiratory tract, yet prolonged or repeated contact may cause high skin sensitization (Schossler et al 2004). Using high doses could cause the release of histamine and prostaglandin, ulcers and gastric mucus secretion changes (Shahmohammadi et al 2016). The genotoxic potential of sodium benzoate associated with chromosomal aberration, sister chromatid exchanges and cell cycle proliferation index analysis in the cultured human peripheral lymphocytes.…”

Section: Introductionmentioning

confidence: 99%

Assessment of Genotоxic Effects of Some Food Additives on Some Human Cancer Cells

Rashad

Abdel-Tawab

Fahmy

et al. 2019

Arab Universities Journal of Agricultural Sciences

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Some food additives commonly used by humans have been recently proved to be mutagenic. It is of significant importance to evaluate their genotoxic effects, since they are frequently consumed by humans in their daily meals. In this study, we investigated the effects of monosodium glutamate (MSG), sodium benzoate (SB) and saffron on human cell lines; lung cancer (A549), breast cancer (MCF7), colon cancer (Caco-3) and normal lung (Wi38) cell line as control. Cytotoxicity of food additives was screened on multiple cell lines and examined by NR assay (Neutral Red assay). The present study focused on the cytotoxic activity of the food additives and its possible underlying mechanisms. The results showed that food additives; MSG, SB and saffron induced profound cytotoxicity in cancer cells of human colon cancer (Caco-3) (IC50 = 33.92, 15.01, 3.98 μg/ml), human breast cancer (MCF7) (IC50 = 12.79, 0.378, 10.73 μg/ml), human lung cancer cell line (A549) (IC50 = 27.37, 0.45, 2.46 μg/ml), respectively. Moreover, food additives exhibited cytotoxic activity on normal lung cell lines (Wi38) (IC50 = 4.25, 0.733, 18.14 μg/ml). These data indicated that food additives decreased cell viability in malignant and nonmalignant cells as well as confirmed the occurrence of their cytotoxic effects.

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An Overview on the Effects of Sodium Benzoate as a Preservative in Food Products

Cited by 53 publications

References 28 publications

Alterations in Oxidative Stress and Antioxidantin Albino rats Treated with Individual and Combined Various Food Additives

Alterations in Oxidative Stress and Antioxidantin Albino rats Treated with Individual and Combined Various Food Additives

Inhibitory effect of Sodium Benzoate as Preservative Material in the Biogas Production in a Batch Anaerobic Digestion Process

Assessment of Genotоxic Effects of Some Food Additives on Some Human Cancer Cells

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