An overview on the application of genus Chlorella in biotechnological processes

Andrade, Cristiano José de; Andrade, Lidiane Maria de

doi:10.15226/2475-4714/2/1/00117

Cited by 42 publications

(20 citation statements)

References 25 publications

(45 reference statements)

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“…[ 3 ] Chlorella genus, and specifically Chlorella vulgaris ( C. vulgaris ) species, was first discovered by M.W. Beijerinck in 1890, but the starting point of industrial production was after 1960 in Japan [ 5 , 6 ]. Today C. vulgaris , along with C. pyrenoidosa and C. luteoviridis , are enlisted in the EU Novel Food Catalog [ 7 ], and Chlorella is commercially used as a food additive, supplement, pigment, food emulsion, and animal feed [ 6 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

Experimental Design and Optimization of Recovering Bioactive Compounds from Chlorella vulgaris through Conventional Extraction

et al. 2021

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Microalgae contain an abundance of valuable bioactive compounds such as chlorophylls, carotenoids, and phenolics and, consequently, present great commercial interest. The aim of this work is the study and optimization of recovering the aforementioned components from the microalgae species Chlorella vulgaris through conventional extraction in a laboratory-scale apparatus using a “green” mixture of ethanol/water 90/10 v/v. The effect of three operational conditions—namely, temperature (30–60 °C), duration (6–24 h) and solvent-to-biomass ratio (20–90 mLsolv/gbiom), was examined regarding the extracts’ yield (gravimetrically), antioxidant activity, phenolic, chlorophyll, and carotenoid contents (spectrophotometric assays), as well as concentration in key carotenoids, i.e., astaxanthin, lutein, and β-carotene (reversed-phase–high-performance liquid chromatography (RP–HPLC)). For this purpose, a face-centered central composite design (FC-CCD) was employed. Data analysis resulted in the optimal extraction conditions of 30 °C, for 24 h with 37 mLsolv/gbiom and validation of the predicted models led to 15.39% w/w yield, 52.58 mgextr/mgDPPH (IC50) antioxidant activity, total phenolic, chlorophyll, and carotenoid content of 18.23, 53.47 and 9.92 mg/gextr, respectively, and the total sum of key carotenoids equal to 4.12 mg/gextr. The experimental data and predicted results were considered comparable, and consequently, the corresponding regression models were sufficiently reliable for prediction.

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Section: Introductionmentioning

confidence: 99%

Experimental Design and Optimization of Recovering Bioactive Compounds from Chlorella vulgaris through Conventional Extraction

et al. 2021

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“…(Chlorophyta, Trebouxiophyceae) are one of the most widely used microalgae in the industrial sector, with an annual production of about 2000 t [1]. In the last decade, microalgae belonging to genus Chlorella have caught scientific attention for their ability to synthesize important nutritional compounds, such as essential amino acids, polyunsaturated fatty acids, carotene, and vitamins [30][31][32]. Microalgae have been consumed in the human diet for thousands of years, and Chlorella spp.…”

Section: Introductionmentioning

confidence: 99%

“…Microalgae have been consumed in the human diet for thousands of years, and Chlorella spp. represents one of the few species utilized as an effective supplementary food [30,33]. Several species of Chlorella have been extensively used commercially over the past 40 years as a food and feed supplement and nutraceuticals [33,34].…”

Section: Introductionmentioning

confidence: 99%

Rapid and Positive Effect of Bicarbonate Addition on Growth and Photosynthetic Efficiency of the Green Microalgae Chlorella Sorokiniana (Chlorophyta, Trebouxiophyceae)

et al. 2020

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Bicarbonate ions are the primary source of inorganic carbon for autotrophic organisms living in aquatic environments. In the present study, we evaluated the short-term (hours) effects of sodium bicarbonate (NaHCO3) addition on the growth and photosynthetic efficiency of the green algae Chlorella sorokiniana (211/8k). Bicarbonate was added to nonaxenic cultures at concentrations of 1, 2, and 3 g L−1 leading to a significant increase in biomass especially at the highest salt concentration (3 g L−1) and also showing a bactericidal and bacteriostatic effect that helped to keep a reduced microbial load in the algal culture. Furthermore, bicarbonate stimulated the increase in cellular content of chlorophyll a, improving the photosynthetic performance of cells. Since microalgae of genus Chlorella spp. show great industrial potential for the production of biofuels, nutraceuticals, cosmetics, health, and dietary supplements and the use of bicarbonate as a source of inorganic carbon led to short-term responses in Chlorella sorokiniana, this method represents a valid alternative not only to the insufflation of carbon dioxide for the intensive cultures but also for the production of potentially bioactive compounds in a short period.

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“…Porphyra umbilicalis (red alga) and Chlorella sp. (microalgae) contain MAAs; hence, acting as sunscreens [16,116]. Other examples include Bifurcaria bifurcata [55], Cladosiphon okamuranus [49], Cystoseira hakodatensis [59], Cystoseira barbata [57], Cystoseira foeniculacea [58], Ecklonia cava [62], Rhodella reticulata [103], and Undaria pinnatifida [70] are algae species that have antioxidant activities.…”

Section: Photo-protectivity and Antioxidant Activitiesmentioning

confidence: 99%

Algae Metabolites in Cosmeceutical: An Overview of Current Applications and Challenges

et al. 2020

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Cosmetics are widely used by people around the world to protect the skin from external stimuli. Consumer preference towards natural cosmetic products has increased as the synthetic cosmetic products caused adverse side effects and resulted in low absorption rate due to the chemicals’ larger molecular size. The cosmetic industry uses the term “cosmeceutical”, referring to a cosmetic product that is claimed to have medicinal or drug-like benefits. Marine algae have gained tremendous attention in cosmeceuticals. They are one of the richest marine resources considered safe and possessed negligible cytotoxicity effects on humans. Marine algae are rich in bioactive substances that have shown to exhibit strong benefits to the skin, particularly in overcoming rashes, pigmentation, aging, and cancer. The current review provides a detailed survey of the literature on cosmeceutical potentials and applications of algae as skin whitening, anti-aging, anticancer, antioxidant, anti-inflammation, and antimicrobial agents. The biological functions of algae and the underlying mechanisms of all these activities are included in this review. In addition, the challenges of using algae in cosmeceutical applications, such as the effectiveness of different extraction methods and processing, quality assurance, and regulations concerning extracts of algae in this sector were also discussed.

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An overview on the application of genus Chlorella in biotechnological processes

Cited by 42 publications

References 25 publications

Experimental Design and Optimization of Recovering Bioactive Compounds from Chlorella vulgaris through Conventional Extraction

Experimental Design and Optimization of Recovering Bioactive Compounds from Chlorella vulgaris through Conventional Extraction

Rapid and Positive Effect of Bicarbonate Addition on Growth and Photosynthetic Efficiency of the Green Microalgae Chlorella Sorokiniana (Chlorophyta, Trebouxiophyceae)

Algae Metabolites in Cosmeceutical: An Overview of Current Applications and Challenges

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