“…Mostly, hereditary factors are determinants of these differences. Identifying patients that carry these factors is very challenging to estimate their effect on the metabolic capacity following that adjust the therapeutic range of drugs doses accordingly (Swen et al, 2011, Mulder et al, 2021, van den Oord et al, 2007, Petersen et al, 1982. By identifying these patients, adverse drug reactions reduced and the response to treatment is improved.…”