An overview of Ebola virus disease

Abstract

Ebola virus disease (EVD), formerly known as Ebola hemorrhagic fever, is a severe, often fatal illness in humans. Ebola virus (EBOV) is transmitted through contact with blood or body fluids of a person who contracted or died from EVD, contaminated objects like needles and infected animals or bush meat. EVD has an incubation period of 2 to 21 days, and the infection has an acute onset without any carrier status. Currently, there is no standard treatment for EVD, so it is important to avoid infection or further spreading of the virus. Although historically the mortality of this infection exceeded 80%, modern medicine and public health measures have been able to lower this figure and reduce the impact of EBOV on individuals and communities. Its treatment involves early, aggressive supportive care with rehydration. Clinicians should consider the possibility of EVD in persons with travel or exposure history with the incubation period presenting constitutional symptoms in order to promptly identify diseased patients, and prevent further spreading of the disease.

Novel and emergent sandfly‐borne phleboviruses in Asia Minor: a systematic review

“…A detailed assessment of content in this cohort revealed that 2 reports were merely focusing on West Nile virus without presenting data on phleboviruses and were subsequently omitted . Review articles that present general or agent‐specific information on vector‐borne infections in Turkey including phleboviruses comprised 7 of the entries, and they were examined for further cited research on phleboviruses. Two reports presented surveillance data on the mosquito‐borne pathogenic phlebovirus Rift Valley fever virus, where serological and nucleic acid tests gave negative results in 350 sera (from cattle, horse, sheep, goat, and water buffaloes) and in aborted fetuses, collected from the Black Sea region of Turkey.…”

The Laboratory Diagnosis of Important Zoonotic Infections

“…Çünkü başlangıç bulguları spesifik değildir ve genellikle sıtma, tifo, menejit, sigelloz ve leptospiroz gibi hastalıklarla karışabilir (24,27,28) .…”

“…Bu antikorlar bitkilerden özellikle nicotiana benthamianadan üretilir. Primatlar üzerinde kısıtlı sayıda yapılan çalışmalarda koruyucu etkisi saptanmıştır (28,29) .…”

Multi Epitope Peptide Vaccine Prediction against Sudan Ebola Virus Using Immuno-Informatics Approaches

“…Ebola virus is belonging to Filoviruses Filoviridae family which is zoonotic pathogen that causes hemorrhagic fever for both human and nonhuman primate with high rate of death that exceeded 80% [1][2][3][4][5][6][7][8]. The first appearance of Ebola virus in Sudan, Yambuku, Nzara and Democratic Republic of Congo was in 1976 than it spread into a village near the Ebola River [2,4].…”

“…The first appearance of Ebola virus in Sudan, Yambuku, Nzara and Democratic Republic of Congo was in 1976 than it spread into a village near the Ebola River [2,4].…”