An Optimized Individual Target Brain in the Talairach Coordinate System

Kochunov, Peter; Lancaster, Jack L.; Thompson, Paul M.; Toga, Arthur W.; Brewer, Patricia; Hardies, Jean; Fox, Peter T.

doi:10.1016/s1053-8119(02)91084-0

Cited by 78 publications

(35 citation statements)

References 25 publications

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“…Peaks of the resulting clusters were labeled by reference to the Talairach Daemon atlas (Lancaster et al . 1997, 2000), and all clusters were displayed on a single‐subject Talairach template (colin27; Kochunov et al . 2002).…”

Section: Methodsmentioning

confidence: 99%

Functional neuroimaging studies of alcohol cue reactivity: a quantitative meta‐analysis and systematic review

2012

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A comprehensive understanding of the neurobiology of alcohol cue reactivity is critical to identifying the neuropathology of alcohol use disorders (AUD) and developing treatments that may attenuate alcohol craving and reduce relapse risk. Functional neuroimaging studies have identified many brain areas in which alcohol cues elicit activation. However, extant studies have included relatively small numbers of cases, with AUD of varying severity, and have employed many different cue paradigms. We used activation likelihood estimation, a quantitative, coordinate-based meta-analytic method, to analyze the brain areas activated by alcohol-related cues across studies, and to examine whether these areas were differentially activated between cases and controls. Secondarily, we reviewed correlations between behavioral measures and cue-elicited activation, as well as treatment effects on such activation. Data analyzed were from 28 studies of 679 cases and 174 controls. Among cases, alcohol cues elicited robust activation of limbic and prefrontal regions, including ventral striatum, anterior cingulate, and ventromedial prefrontal cortex. As compared to controls, cases demonstrated greater activation of parietal and temporal regions, including posterior cingulate, precuneus, and superior temporal gyrus. Cue-elicited activation of ventral striatum was most frequently correlated with behavioral measures and most frequently reduced by treatment, but these results often derived from region-of-interest analyses that interrogated only limbic regions. These findings support long-standing theories of mesolimbic involvement in alcohol cue processing, but suggest that cue-elicited activation of other brain areas may more clearly differentiate cases from controls. Prevention and treatment for AUD should consider interventions that may reduce cue-elicited activation of these areas.

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Section: Methodsmentioning

confidence: 99%

Functional neuroimaging studies of alcohol cue reactivity: a quantitative meta‐analysis and systematic review

2012

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“…A full-width half-maximum (FWHM) of 12 mm, permutation testing with 5000 iterations, a false discovery rate threshold of 0.01, and a cluster extent threshold of 100 mm 3 were applied to the data. Clusters were overlaid on the optimized Colin Brain (Kochunov et al, 2002), and the resulting maps identified the regions of activation common to successful response inhibition in the Go/NoGo task (Fig. 1A) and the Stop-Signal task (Fig.…”

Section: Within-condition Meta-analysismentioning

confidence: 99%

“…Activation likelihood estimation (ALE) map showing significant inhibition-related activation clusters overlaid on the optimized Colin Brain(Kochunov et al, 2002). The left side of the brain is on the left side of the scan.…”

mentioning

confidence: 99%

Are the neural correlates of stopping and not going identical? Quantitative meta-analysis of two response inhibition tasks

2011

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“…First, the structural T1-weighted images were registered to an optimized individual target brain in the Talairach coordinate system (Kochunov et al, 2002) available at the BrainMap website (http://www.brainmap.org/ale/index.html). A rigid body transformation with 6 degrees of freedom (3 translations and 3 rotations) was applied without scaling the brain in order to maintain individual brain sizes.…”

Section: Diffusion-weighted Image Analysis and Tractography-based Segmentioning

confidence: 99%

Callosal tracts and patterns of hemispheric dominance: A combined fMRI and DTI study

2011

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An Optimized Individual Target Brain in the Talairach Coordinate System

Cited by 78 publications

References 25 publications

Functional neuroimaging studies of alcohol cue reactivity: a quantitative meta‐analysis and systematic review

Functional neuroimaging studies of alcohol cue reactivity: a quantitative meta‐analysis and systematic review

Are the neural correlates of stopping and not going identical? Quantitative meta-analysis of two response inhibition tasks

Callosal tracts and patterns of hemispheric dominance: A combined fMRI and DTI study

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