An online questionnaire survey on preferred timing for the diagnosis and management of thyroid carcinoma in general population in Korea

Park, Jin-Woo; Yoo, Jae-Soo; Yun, Jin-Kyung; Kim, Byoung-Hoon; Noh, Yeonwoo; Kim, Dong-Ju

doi:10.4174/astr.2016.90.6.297

Cited by 7 publications

(10 citation statements)

References 20 publications

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“…The American Thyroid Association guidelines (2015 edition) recommend that non-invasive T1/T2 cN0 PTC does not require PCCND, and the 5-year survival rate of patients with active monitoring and active intervention is 98.2% (10). Park et al (25) conducted a questionnaire survey among patients with thyroid cancer after surgery and showed that 69.2% of patients with thyroid cancer approved of the operation with a low recurrence rate and could accept a slight amount of increased risk of complications. Chen et al (26) conducted a retrospective study of 18,376 PTC patients and showed PCCND could better remove potential lymph node metastasis.…”

Section: Discussionmentioning

confidence: 99%

The characteristics and risk factors of central compartment lymph node metastasis in cN0 papillary thyroid carcinoma coexistent with Hashimoto’s thyroiditis

Jin

Liu

et al. 2020

Gland Surg

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Background: Currently, there are few studies on the characteristics of lymph node metastasis in the central region in patients with preoperative negative lymph node (cN0) papillary thyroid carcinoma (PTC) coexistent with Hashimoto's thyroiditis (HT). There is still a significant controversy on whether to perform prophylactic central compartment lymph node dissection for T1/T2 cN0 PTC. Therefore, we aimed to investigate the characteristics and risk factors of central compartment lymph node metastasis in cN0 PTC (T1 or T2 stage) coexists with HT. Methods: From Jun. 2015 to Apr. 2019, the clinicopathological data of 354 patients with stage T1/ T2 cN0 PTC admitted to the thyroid tumor surgery of Inner Mongolia People's Hospital were analyzed retrospectively. All patients underwent central compartment lymph node dissection. According to the results of the postoperative pathological examination, the patients were divided into two groups: PTC group (n=236) and PTC coexistent with the HT group (n=118).Results: The proportion of PTC patients with HT was 33.33% (118/354) in T1/T2 cN0 PTC patients; most of them were women. The levels of serum thyrotropin, antithyroglobulin antibody, and thyroid peroxidase antibody in PTC coexistent with HT group are higher than those in the PTC group (P<0.05).The number of lymphadenectomies in PTC coexistent with HT group was more than that in PTC alone group (P<0.05). Univariate analysis showed that antithyroglobulin antibody positive, tumor diameter >1 cm, and multifocal cancer in T1/T2 stage cN0 PTC coexistent with HT group were all correlated with lymph node metastasis in the central region (P<0.05). Logistic regression analysis showed that tumor diameter >1 cm, and multifocal cancer were the risk factors of central compartment lymph node metastasis in patients with T1/T2 stage cN0 PTC coexistent with HT (P<0.05).Conclusions: HT is not a relevant factor of central lymph node metastasis in T1/T2 cN0 PTC; regardless of the presence or absence of HT, tumor diameter >1 cm and multifocal cancer are risk factors for central lymph node metastasis in patients with T1/T2 cN0 PTC. Therefore, preventive lymph node dissection in the central region should be conducted actively during the operation.

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Section: Discussionmentioning

confidence: 99%

The characteristics and risk factors of central compartment lymph node metastasis in cN0 papillary thyroid carcinoma coexistent with Hashimoto’s thyroiditis

Jin

Liu

et al. 2020

Gland Surg

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“…Cytological evaluation included various parameters likesample adequacy, background, cellular arrangement / pattern, cellular details including nuclear features [5]. A uniform reporting system for thyroid FNA will facilitate effective communication among cytopathologist, endocrinologist, radiologists and surgeons [15]. The Bethesda system of reporting thyroid cytopathology established a uniform tiered reporting system.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of fine needle aspiration cytology of thyroid lesions based on Bethesda system of reporting cytopathology

Chandan

Jigalur

et al. 2019

Trop J Pathol Microbiol

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Introduction: FNAC is the first line diagnostic test for evaluation of thyroid lesions. Identification of cytological features is key element in diagnosing thyroid lesions, which will reduce the number of unnecessary surgeries of thyroid nodules. Bethesda system of reporting helps the clinicians to take appropriate therapeutic intervention. Aim: To study the cytomorphological features of various thyroid lesions and to categorize as per Bethesda system proposed by NCI Bethesda USA in 2007. Materials and Methods: This is a prospective study of cases of thyroid lesions received in cytology section of Department of Pathology, KIMS Hubballi, during Jan 2017 to Dec 2017. FNAC was performed and reported according to Bethesda system. Results: FNAC was performed on 370 cases of thyroid lesions. Maximum number of cases were in the age group of 21-30 years.Male to female ratio was 1: 9.27. Maximum number of cases presented in less than 6 month duration. Most of the cases presented with swelling in the neck. Out of the total 370 cases, 351were benign lesion, 6 cases were malignant, 8 were unsatisfactory, 3 were follicular neoplasm/suspicious of follicular neoplasm, 1 was suspicious for malignancy and 1 was follicular lesions of undetermined significance. Out of 351 benign lesions, commonest was colloid/ nodular goiter, followed by lymphocytic/Hashimotos thyroiditis. Conclusion: FNAC is the most simple, rapid and safe diagnostic test for evaluation of thyroid lesions with high degree of accuracy. Bethesda system of reporting thyroid cytopathology is very useful as it is systematic and standardized and hence provides better communication between clinicians and cytopathologist for appropriate therapeutic intervention.

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“…We employed a self-administered questionnaire which was adapted from a prior study on comparable objectives [3].The questionnaire contains two sections. The first section gathers participants' personal information including age, gender, marital status, education level, monthly household income, and past medical history related to thyroid cancer surgery or history of thyroid cancer surgery.…”

Section: Data Collection Tool and Proceduresmentioning

confidence: 99%

“…The American Thyroid Association's (ATA) new guidelines, as of 2015, advise FNA to be used only when nodules are larger than 1 cm in diameter, even in the presence of sonographic patterns that raise concern. Additionally, they endorse the recommendation of active observation for PTMCs as a viable substitute for immediate surgery [3]. The authors think it is crucial to use shared decision-making.…”

Section: Introductionmentioning

confidence: 97%

The Preferred Route for the Diagnosis and Management of Thyroid Carcinoma Among the General Population in Saudi Arabia

Aldharman¹,

Albalawi²,

Daghistani³

et al. 2023

Cureus

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Background: Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Papillary thyroid microcarcinoma (PTMC) is a specific subgroup of PTC. Given their small size, PTMCs are often asymptomatic and behave benignly. This puts physicians in a challenging situation about how to prevent overdiagnosis and overtreatment of PTMC. This study aimed to assess the preferences regarding the route of PTMC diagnosis and treatment among Saudi Arabia's general population.Methods: This is a cross-sectional questionnaire-based-study conducted among the general population in Saudi Arabia. The target subjects were the general population of Saudi Arabia both genders and different age groups from various regions of Saudi Arabia (Western, Central, Eastern, Southern, and North). Participants who did not complete the questionnaire or did not agree to participate were excluded. A self-administered questionnaire was distributed on different social media platforms to collect data from different regions. Data analysis was conducted by using Statistical Package for the Social Sciences (SPSS) 24.0 version (IBM Inc., Chicago, USA) statistical software. A Chi-square test was used to compare categorical variables.Results: A total of 1,428 participants were included. The majority of them were females (64.4%), and most of them were aged between 19 and 25 years. Moreover, we found that 4.8% of the study population had a medical history of thyroid cancer. Our results revealed that more than half of respondents (54.6%) would select surgical operation immediately if they have a thyroid nodule less than 1 cm in maximal diameter, which turns out to be a PTC. The vast majority of participants (90.1%) would prefer to do cytologic confirmation immediately if they have a thyroid nodule less than 1 cm in maximal diameter, which has suspicious characteristics of PTC in neck ultrasound examination. Regarding PTMC operation, 59.8% of responders were more concerned about complications than recurrences. We found that neither age nor gender significantly affects decision-making for management or operative extent for PTC. There was a significant difference between age and decision-making for the diagnosis of suspicious thyroid nodules (p value = 0.041). Conclusion: Our results concluded that most of the participants preferred to select immediate surgery and cytologic confirmation regarding the management and diagnosis of PTC. More research is advised. The need to inform patients about their disease state and treatment options should be highlighted more.

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An online questionnaire survey on preferred timing for the diagnosis and management of thyroid carcinoma in general population in Korea

Cited by 7 publications

References 20 publications

The characteristics and risk factors of central compartment lymph node metastasis in cN0 papillary thyroid carcinoma coexistent with Hashimoto’s thyroiditis

The characteristics and risk factors of central compartment lymph node metastasis in cN0 papillary thyroid carcinoma coexistent with Hashimoto’s thyroiditis

Evaluation of fine needle aspiration cytology of thyroid lesions based on Bethesda system of reporting cytopathology

The Preferred Route for the Diagnosis and Management of Thyroid Carcinoma Among the General Population in Saudi Arabia

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