An investigation on preliminary phytochemical and safety profiles of methanolic root extract of Curculigo orchioides

Elumalai, A.; Chandiran, Irisappan Sarath; Kadalmani, Balamuthu

doi:10.1016/j.jopr.2013.08.023

Cited by 6 publications

(6 citation statements)

References 9 publications

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“…The plant has been reported to have constituents of phenylpropanoids, flavonoids and phenolic acids, notably, persicarin and isorhamnetin 23 . Preliminary phytochemical screening is commonly performed for the identification of substantial phytochemicals that may be involved in the antioxidant activity of plant extracts [24][25][26] . In the present study, total phenolic content was analyzed in the crude extracts as they are the primary compounds responsible for antioxidant activity.…”

Section: Discussionmentioning

confidence: 99%

Antioxidant Activity, Total Phenolic and Total Flavonoid Content of Oenanthe Javanica Blume (Dc) Collected From Imphal West District

Bhaigyabati¹,

Devi²,

Chvi³

et al. 2017

Int. Res. J. Pharm.

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Oenanthe javanica Blume (DC) is an aromatic medicinal herb having pharmacological properties such as antioxidant, anti-quorum sensing, anticoagulant, antitoxic, hepatoprotective, anti-hepatitis B virus and memory improvement. It is one of the most consumed vegetable throughout the year in Manipur. The present study was carried out to analyze the phytochemical constituents, antioxidant activity and total phenolic and total flavonoid content of Oenanthe javanica. Preliminary phytochemical analysis was done using standard procedure. Total phenolic, total flavonoid content and antioxidant activities were determined spectrophotometrically in crude aqueous and methanolic extracts. Preliminary phytochemical analysis indicates the presence of amino acids, carbohydrates, proteins, flavonoids, phenolic compounds, steroids and terpenoids, saponins, tannins, cardiac glycosides except alkaloids and phlobatannins. The present study demonstrates the antioxidant activity of Oenanthe javanica Blume (DC) due to the various phytochemicals present in the extract which confer their traditional uses as food and medicine.

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Section: Discussionmentioning

confidence: 99%

Antioxidant Activity, Total Phenolic and Total Flavonoid Content of Oenanthe Javanica Blume (Dc) Collected From Imphal West District

Bhaigyabati¹,

Devi²,

Chvi³

et al. 2017

Int. Res. J. Pharm.

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“…Alkaloids were detected only in C. corchoropsis (Table 2). Preliminary phytochemical screening experiments are commonly performed to promote a guidance of substantial phytochemicals that may be involved in the antioxidant activity of plant extracts (Anandakirouchenane et al, 2013;Basma et al, 2011;Das et al, 2012).…”

Section: Resultsmentioning

confidence: 99%

Phytochemical screening, total phenolic content and antioxidant activity of some plants from Brazilian flora

Neto¹,

Uchôa²,

Moura³

et al. 2016

J. Med. Plants Res.

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The present study evaluated the total phenolic and flavonoid content as well as the antioxidant activity of methanolic leaf extracts of five plants from Brazilian flora: Abarema cochliacarpos, Croton corchoropsis, Myroxylon peruiferum, Stryphnodendron pulcherrimum and Tanaecium cyrtanthum by 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS), 2,2-diphenyl-1-picrylhydrazyl (DPPH) and total antioxidant capacity assays. A thin layer chromatography analysis of all plant extracts has also been performed and it showed the presence of different types of secondary metabolites, namely saponins, phenylpropanoids and flavonoids. Among the studied plants, A. cochliacarpos and S. pulcherrimum showed considerable antioxidant radical scavenging activity on all the tested assays and they also exhibited substantial amounts of phenolic compounds. In addition, a positive correlation was found between total phenols and both ABTS radical scavenging activity and total antioxidant capacity assays, thus indicating the major role of phenols on the antioxidant activity of these plants. To the best of the authors' knowledge, this is the first approach where the phenolic content and antioxidant activity of A. cochliacarpos, C. corchoropsis, M. peruiferum, S. pulcherrimum and T. xanthophyllum were explored.

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“…The existence of organic components is thought to be the catalyst for therapeutic activity. According to a study conducted by Anandakirouchenane et al (2013), the methanolic extract was found to contain flavonoids, phenols, glycosides, saponins, terpenoids, and sterols, but not alkaloids or tannins. Similar it showed that cardiovascular glycosides were only found in chloroform and ethanol extracts, while saponins and steroids were absent from chloroform and ethanol extracts (Anandakirouchenane et al, 2013).…”

Section: Phytochemical Analysismentioning

confidence: 99%

Green Synthesis of Silver Nanoparticles using Curculigo orchioides and Evaluation of its Antimicrobial Activity Against ESBL Organism

Usharani¹,

Panneerselvam²,

Flora³

2023

Intern. J. Zool. Invest.

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Extended-spectrum beta-lactamases (ESBL) enzyme producing bacteria are a growing concern in healthcare as these strains are resistant to multiple classes of antibiotics. Development of effective antimicrobial agents against ESBL strain is the major concern of researchers worldwide. Currently nanoparticles have been proposed as a potential treatment of ESBL-producing bacteria. Green synthesis of nanoparticles has several advantages for chemical synthesis. In current study, effect of Curculigo orchioides mediated silver nanoparticles (AgNP) was tested against ESBL producing organisms. The bioactivity of C. orchioides was confirmed by qualitative phytochemical analysis. The synthesized silver nanoparticles were subjected to a series of characterization to confirm its structure and composition. UV visible spectroscopy revealed a strong peak at 390 nm which confirmed the presence of silver nanoparticle. The current FTIR results strongly suggested that the reduction of Ag 2+ to Ag 0+ in the aqueous rhizome extracts was due to a combination of biomolecules. The SEM and TEM analysis revealed that the size and shape was nanoparticle to be 35-39 nm and spherical in shape. The XRD analysis revealed the silver nanoparticle to be crystalline in nature. The antibacterial activity of biosynthesized silver nanoparticles was tested against Escherichia coli and Staphylococcus aureus. The ESBL organisms were resistant to the standard antibiotic ampillicin. Instead, the organisms were susceptible to the silver nanoparticle. The efficiency increased with increase in concentration. This study revealed that several strains had more sensitivity to nanoparticles than others, as seen by the greater zone of inhibition for Gram-positive strain (S. aureus) than for Gram-negative bacteria (E. coli). The C. orchioides synthesized silver nanoparticle is alternative to existing antibiotics which are ineffective in clinical treatments.

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An investigation on preliminary phytochemical and safety profiles of methanolic root extract of Curculigo orchioides

Cited by 6 publications

References 9 publications

Antioxidant Activity, Total Phenolic and Total Flavonoid Content of Oenanthe Javanica Blume (Dc) Collected From Imphal West District

Antioxidant Activity, Total Phenolic and Total Flavonoid Content of Oenanthe Javanica Blume (Dc) Collected From Imphal West District

Phytochemical screening, total phenolic content and antioxidant activity of some plants from Brazilian flora

Green Synthesis of Silver Nanoparticles using Curculigo orchioides and Evaluation of its Antimicrobial Activity Against ESBL Organism

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