2020
DOI: 10.4012/dmj.2019-200
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An introduction of biological performance of zirconia with different surface characteristics: A review

Abstract: Zirconia (ZrO2) ceramic is widely used in dentistry as a clinical dental biomaterial. In this review, we are focusing on and summarizing the biological performance of zirconia under different surface characteristics. We have included an initial tissue cell attachment study on zirconia and bacterial adhesion on zirconia. Our results suggest that surface modifications applied on zirconia may change the interfacial surface characteristics e.g. surface roughness, surface free energy, and chemistry of zirconia. The… Show more

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Cited by 20 publications
(15 citation statements)
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References 106 publications
(117 reference statements)
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“…Furthermore, relevant studies demonstrate that the main factors of bacterial adhesion to ZrO 2 surfaces are its electrostatic state, as well as wetting properties [ 18 , 109 ] The interaction of chemical bonds between the extracellular membrane of bacteria and free radicals on the implant surface providess the necessary connection for the formation of a faster biofilm [ 18 ]. Thus, a great number of technologies have been researched and developed to combat the biofilm formed after installing the dental component in the oral environment as well as for cleaning and sterilization processes [ 18 , 110 ].…”
Section: Biological Responsesmentioning
confidence: 99%
“…Furthermore, relevant studies demonstrate that the main factors of bacterial adhesion to ZrO 2 surfaces are its electrostatic state, as well as wetting properties [ 18 , 109 ] The interaction of chemical bonds between the extracellular membrane of bacteria and free radicals on the implant surface providess the necessary connection for the formation of a faster biofilm [ 18 ]. Thus, a great number of technologies have been researched and developed to combat the biofilm formed after installing the dental component in the oral environment as well as for cleaning and sterilization processes [ 18 , 110 ].…”
Section: Biological Responsesmentioning
confidence: 99%
“…Different parameters such as cell spreading, cell proliferation, cell viability or expression of a wide range of inflammation or osteogenic differentiation genes were evaluated. Reviews considering in vitro data of cell studies mainly compared zirconia with titanium surfaces [ 20 , 21 ], and only limited information is available about the influence of surface topography on cell behavior [ 22 ].…”
Section: Introductionmentioning
confidence: 99%
“…High-performance ceramics provide good foundations for developing high strength all-ceramic dental materials, of which yttriastabilized zirconia (YSZ) has been under intensive focus recently in the field of dentistry [4][5][6][7][8][9][10][11][12][13]. This material can be toughened by stress-induced transformations and has relatively higher strength and toughness than alumina ceramics.…”
Section: Introductionmentioning
confidence: 99%