An insight into primary biliary cholangitis and its recent advances in treatment: semi-synthetic analogs to combat ursodeoxycholic-acid resistance

Pyridine Moiety: Recent Advances in Cancer Treatment

“…Additionally, pyridines are a class of both synthetically and naturally occurring heterocyclic compounds and its nucleus is a well-studied six membered heterocyclic moiety with a wide range of biological and therapeutic applications [13][14][15] . Moreover, the current interest in the development of new anticancer agents can be partially ascribed to the increasing appearance of multidrug resistance and adverse side effects are a serious threat to public health [16][17][18] . Therefore, the development of new and efficacious medications is a very significant goal and most of the researcher's efforts in this field are directed towards the design of new agents.…”