An innovative reversed-phase monolithic column modified with 4-vinylbiphenyl and ionic liquid stationary phases for capillary electrochromatography

Abstract

A poly(VBP-co-EDMA-co-IL) monolithic column was used for electrochromatographic separation.

Preparation of Benzyl Quinine-modified Monolithic Column for Reversed-phase Capillary Electrochromatography

“…Reversed-phase chromatography is a versatile and popular method in separation sciences. In high performance liquid chromatography (HPLC) and capillary electrochromatography (CEC), it has very wide applications, such as for pharmaceutical analysis, 1,2 food analysis, [3][4][5] environment analysis 6 and biological analysis. 7 CEC is a micro-scaled separation technique, which combines the high efficiency of capillary electrophoresis (CE) and high selectivity of HPLC.…”

“…They have exhibited great application potential because of the advantages of ease of preparation, high column efficiency, high selectivity and good pH stability. [10][11][12] The common monolithic stationary phases with reversed-phase mode mainly include C18, 13 C12, 14 C4, 15 styrene, 16,17 4-vinylbiphenyl, 5,6 and graphene oxide. 18 CEC with monolithic stationary phase mentioned above has been successfully applied for the separation of polycyclic aromatic hydrocarbons (PAHs), alkylbenzenes, amino acids, phenols, anilines, food additives, etc.…”

“…Because of the introduction of charged functional monomers, the new type styrene-based 16,17 and vinylbiphenyl-based 5,6 reversed-phase monolithic columns make a compromise between the amount of organic phase and the excellent reversedphase selectivity. For the separation of various compounds with different polarity, the amount of organic phase decreases to 40%.…”