An innovative approach to use zeolite as crosslinker for synthesis of p(HEMA-co-NIPAM) hydrogel

Durmuş, Seçil; Yılmaz, Baran; Onder, Alper; Ilgın, Pınar; Özay, Hava; Özay, Özgür

doi:10.1007/s00706-022-02908-w

Cited by 10 publications

(4 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Additionally, the peaks at 1048–1146 cm −1 in the spectrum of p(HEMA-co-NIPAM) result from C-O-C stretching vibrations. Notably, similar results have been reported in the literature for FTIR spectra of p(HEMA-co-NIPAM) hydrogels [ 32 , 33 ].…”

Section: Resultssupporting

confidence: 89%

Evaluation of p(HEMA-co-NIPAM) hydrogels for removal of methylene blue from aqueous solution:isotherm, kinetic, and thermodynamic studies

MİNE ANTEP,

NALAN DEMİR,

HIZLIATEŞ

et al. 2024

Turkish Journal of Chemistry

View full text Add to dashboard Cite

In this study, a novel adsorbent material, poly (2-hydroxyethyl methacrylate-co-N-isopropyl acrylamide) (p(HEMA-co-NIPAM) hydrogel, was synthesized for the purpose of removing methylene blue (MB) from aqueous media. The synthesis of hydrogel was carefully conducted, and its properties were thoroughly examined using techniques such as Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and thermogravimetric analysis (TGA). The adsorption experiments conducted revealed a remarkable affinity of p(HEMA-co-NIPAM) hydrogel towards MB. The highest adsorption was observed when 0.05 g of the adsorbent were utilized, with optimal conditions at a pH of 6.0 and a temperature of 15 °C. This underscores the importance of pH control and temperature regulation in optimizing the adsorption treatment. The adsorption behavior of MB on p(HEMA-co-NIPAM) hydrogel was best elucidated by the Langmuir isotherm model, which provided insights into the maximum adsorption capacity. Impressively, this capacity reached 126.6 mg/g, indicative of the adsorbent's robust capability to capture the MB molecules. The isotherm data further highlighted the strong affinity between p(HEMA-co-NIPAM) hydrogel and the MB dye, underscoring the effectiveness of the synthesized hydrogel as an adsorbent material. The successful application of p(HEMA-co-NIPAM) hydrogel for MB adsorption not only emphasizes its potential for wastewater treatment but also hints at its broader significance for environmental remediation. By harnessing the adsorption capabilities of this hydrogel, the removal of MB from industrial and domestic wastewater could be significantly enhanced, leading to cleaner water resources. This study presents p(HEMA-co-NIPAM) hydrogel as a promising adsorbent material with exceptional affinity for MB. This is demonstrated through a comprehensive analysis of its synthesis, characterization, and adsorption performance. The findings hold promise for addressing wastewater contamination issues and promoting sustainable water management practices.

show abstract

Section: Resultssupporting

confidence: 89%

Evaluation of p(HEMA-co-NIPAM) hydrogels for removal of methylene blue from aqueous solution:isotherm, kinetic, and thermodynamic studies

MİNE ANTEP,

NALAN DEMİR,

HIZLIATEŞ

et al. 2024

Turkish Journal of Chemistry

View full text Add to dashboard Cite

show abstract

“…When the FC reagent was loaded, the surface area of AH increased from 0.336 to 4.148 m 2 g –1 ; moreover, the average pore sizes of AH and AH-FC were 6.23 and 11.95 nm, respectively. Once the hydrogel was formed, loading of the heteropolyanionic FC reagent imparted it a nanolayer structure with large intersecting pores; hence, there was an increase in hydrogel porosity and surface area of AH-FC hydrogels . In the AH-FC hydrogel interacting with the CFA antioxidant, the surface area decreased from 4.148 to 0.118 m 2 g –1 as the majority of the pores were filled with antioxidant molecules.…”

Section: Resultsmentioning

confidence: 99%

“…Once the hydrogel was formed, loading of the heteropolyanionic FC reagent imparted it a nanolayer structure with large intersecting pores; hence, there was an increase in hydrogel porosity and surface area of AH-FC hydrogels. 34 In the AH-FC hydrogel interacting with the CFA antioxidant, the surface area decreased from 4.148 to 0.118 m 2 g −1 as the majority of the pores were filled with antioxidant molecules. In addition, because too much antioxidant entered the pores, the pore size increased from 11.95 to 16.74 nm.…”

Section: ■ Introductionmentioning

confidence: 99%

Folin–Ciocalteu Reagent-Loaded Acrylamide-Based Hydrogel Sensor for Antioxidant Capacity Measurement with the Molybdenum Green Method

Yermeydan Peker,

Koç,

Üzer

et al. 2024

ACS Appl. Polym. Mater.

View full text Add to dashboard Cite

The widely known Folin−Ciocalteu (FC) method of total antioxidant capacity (TAC) measurement of phenolic compounds (including phenolic antioxidants) operates only in the solution phase. In this study, a Folin−Ciocalteu sensor, which functions on a solid surface, was developed for the first time as an antioxidant capacity determination method. First, an acrylamide-based transparent hydrogel (AH) was synthesized, and the Folin−Ciocalteu reagent was loaded into this hydrogel to obtain a yellow sensor material (AH-FC). The structure of AH-FC was characterized by infrared (IR), scanning-transmission electron microscopy/ energy dispersion X-ray spectrometry (STEM-EDX), X-ray photoelectron spectroscopy (XPS), thermogravimetric analysis (TGA), and Brunauer− Emmett−Teller (BET) surface analysis techniques. AH-FC, whose structure was elucidated, interacted with different phenol-and amine-type antioxidants to obtain a green color, different from the starting yellow color. The reason for the color change is thought to arise from the reduction of the molybdenum atom in the structure of the FC reagent from the (+6) oxidation state to the (+5) oxidation state in acidic medium, known as the "molybdenum green" method. The color change in the AH-FC structure was measured with the help of a smartphone application. In selectivity experiments with different phenolic compounds, as opposed to the classical Folin−Ciocalteu method, AH-FC responds only to antioxidants, making AH-FC even more important. Additionally, in experiments conducted in the presence of different cations, anions, sugars, and amino acids, AH-FC responds to antioxidants with a high recovery value of 94.6 to 104.0%. AH-FC applied to real samples of green tea, thyme, apple juice, and red wine was able to determine caffeic acid (CFA) with quantitative recovery in samples supplemented with a caffeic acid standard. Caffeic acid was determined in green tea extract using both the suggested AH-FC and the reference CUPRAC, FRAP, and DPPH methods, and the assay was validated through statistical t-and F-tests.

show abstract

“…In drug release, most of the characteristics of a carrier material are required, such as biocompatibility, nontoxic immunogenicity deficiency, repeatability, and continuous activation to the target [ 12 ]. Stimulant-sensitive hydrogels that show great potential in a variety of pharmaceutical and biomedical applications have been one of the latest advances in carrier materials science [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

Release of nifedipine, furosemide, and niclosamide drugs from the biocompatible poly(HEMA) hydrogel structures

YILMAZ¹

2022

Turkish Journal of Chemistry

View full text Add to dashboard Cite

The primary aim of this article was to improve the solubility and bioavailability of the drugs nifedipine, niclosamide, and furosemide due to their poor solubility and dissolution rate. Therefore, these drugs require improvement in solubility and dissolution rate in formulation development, especially in solid dosage forms such as hydrogels and capsules. Hydrogel structures were synthesized by using a biocompatible, nontoxic, and protective pure 2-hydroxy ethyl methacrylate (HEMA) monomer. These hydrogel structures were characterized by various techniques such as scanning electron microscopy and Fourier-transformed infrared spectroscopy. In the next step, drug molecules were loaded in the poly (HEMA) hydrogels. Drug releases of drug-loaded hydrogel structures were measured at certain time intervals and recorded cumulatively (%). The pH affinity, morphology, structure, drug release, swelling, and cytotoxic effect of the resulting materials were studied in detail. In addition to investigating the biocompatibility and cytotoxicity of the poly (HEMA) hydrogel, we evaluated an in vitro cytotoxicity assay on MCF-7and MIA PaCa-2 and HEK 293 cell lines with the hydrogel structure and confirmed cell viability of over 85%. These results suggest that our HEMA polymeric hydrogel is a material with biological importance and great pharmacological potential as a supporting material in the drug release of nifedipine, furosemide, niclosamide, and similar drug molecules.

show abstract

An innovative approach to use zeolite as crosslinker for synthesis of p(HEMA-co-NIPAM) hydrogel

Cited by 10 publications

References 53 publications

Evaluation of p(HEMA-co-NIPAM) hydrogels for removal of methylene blue from aqueous solution:isotherm, kinetic, and thermodynamic studies

Evaluation of p(HEMA-co-NIPAM) hydrogels for removal of methylene blue from aqueous solution:isotherm, kinetic, and thermodynamic studies

Folin–Ciocalteu Reagent-Loaded Acrylamide-Based Hydrogel Sensor for Antioxidant Capacity Measurement with the Molybdenum Green Method

Release of nifedipine, furosemide, and niclosamide drugs from the biocompatible poly(HEMA) hydrogel structures

Contact Info

Product

Resources

About