An Inflammatory Pseudotumor Arising from Pterygopalatine Fossa with Invasion to the Maxillary Sinus and Orbital Cavity

Abstract

We report a patient who had an inflammatory pseudotumor (IPT) that invaded to the maxillary sinus and orbital cavity, with the left pterygopalatine fossa as the principal site; this is a very rare case. The patient was an 83-year-old woman who suddenly became aware of impairment in the eyesight and visual field of the left eye. CT images showed a neoplastic lesion that invaded to the maxillary sinus and orbital cavity, with the left pterygopalatine fossa as the principal site, and also showed contrast effects. To obtain a definitive diagnosis from histopathological analysis, the lesion was biopsied, and she was diagnosed as the inflammatory pseudotumor with the immunohistochemical study and multiplex polymerase chain reaction-based clonality assays. The patient had a lymphoid-predominant lesion that responded to radiotherapy but corticosteroids were not effective. It is important to scrutinize the pathology to avoid unnecessary and mutilating surgery.

Polypoid Carcinoma of the Oropharynx with Stromal Ossifying Myofibroblastic Proliferation: A Case Report and Literature Review

“…PMPs are similar to nodular fasciitis in its various expressions (proliferative fasciitis, proliferative myositis, and ossificans) [19, 21] and from time to time are labeled under various designations such as visceral fasciitis, pseudosarcomatous fibromyxoid tumor [19], spindle cell pseudomalignant proliferation, postoperative spindle cell nodule [23], and inflammatory pseudotumor [18]. These lesions most often occur in the genitourinary system (bladder, prostate, ureter, vagina, and vulva) [24–26] but can occasionally arise in the gastrointestinal tract [27, 28] or in the organs of the upper aerodigestive tract (pharynx, larynx, nasal cavities, and mouth) [29, 30]. They should be clearly distinguished from the inflammatory myofibroblastic tumor (IMT) [31, 32], and for this reason the confusing adjective inflammatory should be avoided in their description.…”