An Induced Carcinoma in the Fowl

Induction of Multiple Primary Tumours in Fowls with 2-Acetamidofluorene

“…The present paper, together with those of Bielschowsky and Green (1945), and Peacock and Peacock (1949,1954) demonstrates that, as in mammals, it is possible to induce multiple primary tumours in various organs of the fowl by means of a carcinogen. Some of these tumours were adenomatous, others frankly malignant, as proved by remote metastases and implantations.…”

Chemical Carcinogenesis in Birds. A Review

“…Sannie et al (1935) applied 1,2benzopyrene to the skin of chickens, but failed to produce tumors. An anaplastic renal carcinoma was observed in one of five Rhode Island Red cocks maintained for 46 weeks on a mixed diet to which was added 2-acetylaminofluorene (Bielschowsky and Green, 1945). reported ulcerated squamous carcinoma of the crop in two chickens after 14 and 17 months of experiment.…”