An independent evaluation of the age-related eye disease study (AREDS) cataract grading system

Braccio, Laura; Camparini, Monica; Graziosi, P; Baratta, G. B.; Ferrigno, Luigina; Williams, Sally L.; Rosmini, Francesco; Sperduto, Robert D.; Maraini, G

doi:10.1076/ceyr.17.1.53.5259

Cited by 6 publications

(3 citation statements)

References 2 publications

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“…Although photographic image analysis densitometry, [14][15][16][17] or digital image analysis [18][19][20] as it becomes more widespread, might provide some more objective measures to enhance our preoperative assessment of cataracts and facilitate studies on progression of lens opacities, 21 the LOCSIII and other cataract grading systems have been shown to have high inter-observer and intra-observer repeatability 13,18,[22][23][24] and to demonstrate some consistency between different classifications. [24][25][26][27] New techniques such as photon spectroscopy for in vivo analysis of lenses remain to be further investigated.…”

Section: Discussionmentioning

confidence: 99%

The relationship between nuclear colour and opalescence on the LOCSIII scale and physical characteristics of cataract nuclei

Smith

El-Brawany

Nassiri

et al. 2002

Eye

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Purpose To evaluate the compression characteristics of the human lens nucleocortex in relation to its LOCSIII clinical grading. Methods Sixteen subjects undergoing planned extracapsular cataract surgery had pre-operative slit-lamp examination and assessment of cataract LOCSIII grade followed by postoperative in vitro evaluation of the nucleus with measurement of 'linear compressibility' by a purpose-designed caliper incorporating a strain gauge, enabling the derivation of a graph of nuclear compression (D (mm) against applied force (F (N)). Results Nuclear colour correlates with the force required to compress a lens to 75% of its original depth (F75) (R = 0.625, P = 0.017). Nuclear opalescence correlates with the force required to compress a lens to 75% of its original depth (R = 0.651, P = 0.012) and inversely with linear compressibility (⌬D/⌬F, the slope of the graph of nuclear compression against applied force) (R = ؊0.610, P = 0.014). F75 is a direct and linear compressibility is an inverse related parameter of lens nucleus 'hardness'. Conclusion A new instrument is described which allows measurement of 'hardness'-related compression characteristics of the human cataract in vitro. There is a relationship between the LOCSIII clinical classification of nuclear cataracts and mechanical compression characteristics of the cataractous lens. LOCSIII classification may aid the preoperative planning of an appropriate surgical approach to an individual cataract.

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Section: Discussionmentioning

confidence: 99%

The relationship between nuclear colour and opalescence on the LOCSIII scale and physical characteristics of cataract nuclei

Smith

El-Brawany

Nassiri

et al. 2002

Eye

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“…[18][19][20][21][22] The comprehensive ophthalmologic examination also included slitlamp examinations to evaluate the anterior chamber, including any cellular infiltrate or flare, lens opacification and/or cataracts (ie, nuclear sclerosis, cortical spoking, posterior subcapsular) using the AREDS grading protocol, IOP using Goldmann applanation tonometry or Tono-Pen (Reichert Ophthalmic Instruments, Depew, New York), 23 and dilated funduscopy. 14 The ERGs were recorded at all centers on the Espion E 2 ERG instrument using Dawson-Trick-Litzkow (DTL)-Plus electrodes (both by Diagnosys LLC, Lowell, Massachusetts) and following the International Society for Clinical Electrophysiology of Vision (ISCEV) protocol for full-field (Ganzfeld) ERGs. 24 The ERG instrument used a light-emitting diode flash that had a flash-to-flash intensity variability of approximately 1%.…”

Section: Assessmentsmentioning

confidence: 99%

Retinal Effects of 6 Months of Daily Use of Tadalafil or Sildenafil

Cordell¹,

Maturi²,

Costigan³

et al. 2009

Arch Ophthalmol

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“…There are various published grading scales that could then potentially be used to sub classify variation and abnormalities of each structure (e.g. lens 20,21 ) however further work including a literature review would be required to determine the most appropriate for primary care optometry.…”

Section: Clinical Signs Found In Anterior Eye Examinationmentioning

confidence: 99%

A proposed minimum data set for international primary care optometry: a modified Delphi study

Davey

Slade

Shickle

2017

Ophthalmic Physiologic Optic

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Purpose: To identify a minimum list of metrics of international relevance to public health, research and service development which can be extracted from practice management systems and electronic patient records in primary optometric practice. Methods: A two stage modified Delphi technique was used. Stage 1 categorised metrics that may be recorded as being part of a primary eye examination by their importance to research using the results from a previous survey of 40 vision science and public health academics. Delphi stage 2 then gauged the opinion of a panel of seven vision science academics and achieved consensus on contentious metrics and methods of grading/classification. Results: A consensus regarding inclusion and response categories was achieved for nearly all metrics. A recommendation was made of 53 metrics which would be appropriate in a minimum data set. Conclusions: This minimum data set should be easily integrated into clinical practice yet allow vital data to be collected internationally from primary care optometry. It should not be mistaken for a clinical guideline and should not add workload to the optometrist. A pilot study incorporating an additional Delphi stage prior to implementation is advisable to refine some response categories.

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An independent evaluation of the age-related eye disease study (AREDS) cataract grading system

Cited by 6 publications

References 2 publications

The relationship between nuclear colour and opalescence on the LOCSIII scale and physical characteristics of cataract nuclei

The relationship between nuclear colour and opalescence on the LOCSIII scale and physical characteristics of cataract nuclei

Retinal Effects of 6 Months of Daily Use of Tadalafil or Sildenafil

A proposed minimum data set for international primary care optometry: a modified Delphi study

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