An In-vitro Evaluation of Retention,  Colonization and Penetration of  Commonly Used Denture Lining  Materials By  Candida albicans

Krishnamurthy, Sushma

doi:10.7860/jcdr/2016/20892.8665

Cited by 15 publications

(34 citation statements)

References 21 publications

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“…Skupien et al [ 24 ] reported that denture cleansers or irradiation with microwave energy decreased yeast counts on the surfaces, but complete elimination was not always reached. Additionally, in vitro studies proved that Candida albicans ( C. albicans ) colonize the surface and penetrate into silicone soft lining materials, which was first reported by Bulard et al [ 25 ] and later confirmed by other studies [ 19 , 26 ]. These results suggested that the efficacy of typical cleaning agents might be limited, because the central section of denture soft linings can be a reservoir of Candida blastopores and hyphae forms [ 3 ].…”

Section: Introductionmentioning

confidence: 67%

Effect of Silver-Emitting Filler on Antimicrobial and Mechanical Properties of Soft Denture Lining Material

et al. 2018

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Colonization of silicone-based soft lining materials by pathogenic yeast-type fungi is a common problem associated with the use of dentures. In this study, silver sodium hydrogen zirconium phosphate (SSHZP) was introduced into polydimethylsiloxane-based material as an antimicrobial filler at concentrations of 0.25, 0.5, 1, 2, 4, 6, 8, 10, 12, and 14% (w/w). The in vitro antimicrobial efficacy was investigated. Candida albicans was used as a characteristic representative of pathogenic oral microflora. Staphylococcus aureus and Escherichia coli were used as the typical Gram-positive and Gram-negative bacterial strains, respectively. The effect of filler addition on the Shore A hardness, tensile strength, tensile bond strength, sorption, and solubility was investigated. An increase in the filler concentration resulted in an increase in hardness, sorption, and solubility, and for the highest concentration, a decrease in bond strength. The favorable combination of antimicrobial efficacy with other properties was achieved at filler concentrations ranging from 2% to 10%. These composites exhibited mechanical properties similar to the material without the antimicrobial filler and enhanced in vitro antimicrobial efficiency.

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Section: Introductionmentioning

confidence: 67%

Effect of Silver-Emitting Filler on Antimicrobial and Mechanical Properties of Soft Denture Lining Material

et al. 2018

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“…Numerous studies have proved the varied effectiveness of removing microorganisms from the surface of prosthetic materials, for example, by using chlorhexidine gluconate, guanidine solution, peroxides, irradiation microwaves, or buy brushing with toothpaste, but these methods result in the loss of various functional properties, including increased roughness [17][18][19][20][21][22], which can facilitate the recolonization of prosthetic materials [23]. It should be emphasized that there are studies questioning the possibility of fully effective removal of microorganisms from the denture using mechanical or chemical cleaning methods [24], suggesting the possibility of penetration of C. albicans into the interior of acrylic materials [25][26][27] which indicates limited disinfection possibilities. Due to the problems associated with colonization by Candida species, investigations related with the development of new materials are being conducted in two directions: the introduction of additional monomers with antimicrobial properties and the manufacturing of composites by introducing the fillers with antimicrobial properties [28].…”

Section: Introductionmentioning

confidence: 99%

Effect of Antibacterial Silver-Releasing Filler on the Physicochemical Properties of Poly(Methyl Methacrylate) Denture Base Material

Chladek

Pakieła

et al. 2019

Materials

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Colonization of polymeric dental prosthetic materials by yeast-like fungi and the association of these microorganisms with complications occurring during prosthetic treatment are important clinical problems. In previously presented research, submicron inorganic particles of silver sodium hydrogen zirconium phosphate (S-P) were introduced into poly(methyl methacrylate) (PMMA) denture base material which allowed for obtaining the antimicrobial effect during a 90 day experiment. The aim of the present study was to investigate the flexural strength, impact strength, hardness, wear resistance, sorption, and solubility during three months of storage in distilled water. With increasing S-P concentration after 2 days of conditioning in distilled water, reduced values of flexural strength (107-72 MPa), impact strength (18.4-5.5 MPa) as well as enhanced solubility (0.95-1.49 µg/mm 3 ) were registered, but they were at acceptable levels, and the sorption was stable. Favorable changes included increased hardness , flexural modulus (2.9-3.3 GPa), and decreased volume loss during wear test (2.9-0.2 mm 3 ). The percentage changes of the analyzed properties during the 90 days of storage in distilled water were similar for all materials.

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“…There are many reports suggest that most of the patients who wear removable dentures can suffer from denture stomatitis 5, 6, 7, 8. Denture relining materials are permanently used for sensitive patients to limit the traumatic effect of dentures by providing cushioning effect and also for denture relining to evenly distribute the loads transferred onto soft tissues during motion 9, 10. They are primarily used in patients with thin atrophic mucosa, with normal mucosa with an atrophied ridge, with a sharp alveolar ridge and when the mucosa exhibits a low tolerance to the load applied by the dentures 11, 12…”

Section: Introductionmentioning

confidence: 99%

“…Denture disinfectant agents such as chlorhexidine gluconate, sodium hypochlorite, hydrogen peroxide and more were reported to cause unfavourable changes to the physical and chemical properties of the soft liner 14, 15. Studies have reported that the fungi and bacterial species can enter porous spaces within the denture liner and that their colonization may reduce the intra-oral life of the material 9, 16. Antibiofilm activity of the soft liner is also an efficient feature to prevent the patients from infections with resident oral microorganisms 17 .…”

Section: Introductionmentioning

confidence: 99%

Functional denture soft liner with antimicrobial and antibiofilm properties

Baygar

Uğur

Balci

et al. 2018

Journal of Dental Sciences

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Background/purpose Denture soft liners, especially used for elders who have poor disinfection habits, provide a favourable environment for accumulation and colonization of microorganisms. This in vitro study is aimed to investigate the effectiveness of natural carvacrol incorporation into soft lining material on the inhibition of oral pathogens. Materials and methods Antimicrobial susceptibility of carvacrol was primarily determined by disc diffusion method. Soft lining material was prepared as recommended by the manufacturer and 10 μL carvacrol was added aseptically to the soft liner discs. Inhibition zones for the control discs without carvacrol (C) and carvacrol-incorporated discs (CL) were determined by disc diffusion method. The biofilm inhibition percentages of carvacrol on soft liner was determined by MTT assay and also observed by Scanning Electron Microscopy (SEM). Results Carvacrol displayed great antimicrobial activity for yeast, Gram-negative and Gram-positive strains. The highest inhibition zone of carvacrol (41.33 ± 1.53 mm) was measured for Bacillus subtilis strain which is followed by Candida albicans and Streptococcus sanguis (34.00 ± 1.73 mm and 32.33 ± 0.58 mm, respectively). The inhibition zones were also similar for soft liner discs with carvacrol, with the highest inhibition zones against B. subtilis , Streptococcus mutans and C. albicans (43.67 ± 0.58 mm, 40.33 ± 0.58 mm and 38.33 ± 1.15 mm, respectively). Incorporation of carvacrol into the soft liner decreased (98.03 ± 0.2%) of the biofilm formation for C. albicans . Conclusion Carvacrol-incorporation obviously decreased the colonization and plaque formation of oral pathogens, especially C. albicans accumulation. Carvacrol may be useful as a promising agent for antibacterial and antifungal management for denture soft lining materials.

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An In-vitro Evaluation of Retention, Colonization and Penetration of Commonly Used Denture Lining Materials By Candida albicans

Abstract: a) Smoother surfaces retain fewer cells than rough surfaces; b) Denture lining materials permit infiltration of through their structure; c) Denture lining materials have insignificant anti-fungal properties.

Cited by 15 publications

References 21 publications

Effect of Silver-Emitting Filler on Antimicrobial and Mechanical Properties of Soft Denture Lining Material

Effect of Silver-Emitting Filler on Antimicrobial and Mechanical Properties of Soft Denture Lining Material

Effect of Antibacterial Silver-Releasing Filler on the Physicochemical Properties of Poly(Methyl Methacrylate) Denture Base Material

Functional denture soft liner with antimicrobial and antibiofilm properties

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