An in vitro biomechanical comparison of Cadisc™-L with natural lumbar discs in axial compression and sagittal flexion

McNally, Donal; Naylor, Jason F; Johnson, Scott A.

doi:10.1007/s00586-012-2249-4

Cited by 18 publications

(24 citation statements)

References 23 publications

(20 reference statements)

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“…The range of motion of L4-L5 intervertebral CAdisc in IMP model was reduced by 50% in flexion-extension and 33% in lateral-bending (Table 3). This demonstrates that the range of motion is less affected due to implantation of Cadisc as compared to other artificial discs (McNally et al, 2012). The FEM-predicted intradiscal pressure and von-Mises stress of L4-L5 along a straight path in an anterior-posterior direction, belonging to the mid-sagittal plane, shows good agreement between Our FEM-predicted results of IMP and INT models (Figs.…”

Section: Cadisc-l Implantationsupporting

confidence: 66%

“…The Cadisc-L is produced from a polyurethane-polycarbonate polymer using stiff endplates. The internal structure of Cadisc-L consists of a soft nucleus encircled by a stiffer annulus that is segregated by a gradual transition of modulus (Naylor et al, 2012;; Barnes et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

“…The advantage of having separated regions is to eliminate sharp interfaces among materials with different mechanical properties . The design of the implant nearly imitates the mechanical properties of the natural disc (Naylor et al, 2012;Johnson et al, 2011;Benzel et al, 2011). Langrana et al (1991).…”

Section: Introductionmentioning

confidence: 99%

“…They revealed a natural disc annulus design that is very comparable to natural disc behavior. There are several investigations on intervertebral discs for healthy and pathologic cases mainly experimentally (Brown et al, 1957;Adams et al, 1980;Tencer et al, 1982;Twomey & Taylor, 1983;Goel et al, 1985;Miller et al, 1986;McNally et al, 2012). This investigation aims to apply FEM analysis to both natural and artificial intervertebral discs (Cadisc-L embedded between L4, L5) using a fiber-reinforced constitutive formulation (Holzapfel & Stadler, 2006).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Finite element analysis of fibre-reinforced constitutive formulation of Cadisc-L

Ansari¹,

Bahraseman²,

Mohssenzadeh³

et al. 2019

10.5267/j.esm

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The current study measures the mechanical behavior of both natural and the monobloc elastomeric disc prosthesis (Cadisc TM-L) by employing a finite element method (FEM) to study the fiberreinforced constitutive formulation provided in the literature. The three-dimensional geometry was created by computed tomography (CT) scan imaging technique. Frontal pure rotational, sagittal, and axial momentum of 7.5 N•m were applied on the top of L3 while the lower half of the L5 was fixed in all directions. This investigation was performed considering two stages: (1) intact L3-L5 lumbar spine (INT model), and (2) Cadisc implemented between L4 and L5 (IMP model). The numerical results for the INT model were validated by experimental data from the literature. Several parameters including the inter-segmental rotation, range of motion in flexion-extension, axial rotation and lateral bending were analyzed. Our numerical results show that the IMP model has a 50% reduction in the 'range of motion' and a 33% reduction in flexion in lateral bending compared to the INT model. These outcomes of this paper reveal the feasibility of applying a fibrereinforced constitutive formulation to generate an accurate three-dimensional FEM model.

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Section: Cadisc-l Implantationsupporting

confidence: 66%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Finite element analysis of fibre-reinforced constitutive formulation of Cadisc-L

Ansari¹,

Bahraseman²,

Mohssenzadeh³

et al. 2019

10.5267/j.esm

View full text Add to dashboard Cite

show abstract

“…McNally et al ( 30 ) anchored a multi-hardness elastic nucleus composed of polycarbonates in various degrees on the upper and lower titanium plates. This modification allowed the implanted segments to rotate by continuously centering on the physiological rotation axis.…”

Section: Discussionmentioning

confidence: 99%

Biomechanical effects of semi-constrained integrated artificial discs on zygapophysial joints of implanted lumbar segments

Zheng

Yao

et al. 2013

Experimental and Therapeutic Medicine

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This study aimed to optimize the design and application of semi-constrained integrated artificial discs (SIADs) using a finite element (FE) analysis following implantation, wherein the zygapophysial joints of the segment were biomechanically reconstructed. An FE model of the L4–L5 segment was constructed. Variations in the stresses on the discs and zygapophysial joints were observed during 5° anteflexion, 5° extension and 5° rotation under the 400-N applied axial load. Stresses and load translation analyses of the discs and zygapophysial joints were conducted during anteflexion, extension and rotation under the 400-N applied axial load. Following implantation of the lumbar segments, the stresses on the SIAD zygapophysial joints were not significantly different from those of physiological discs during anteflexion, and these were both marginally greater compared with those of non-constrained artificial discs (NADs). During extension, the increase in the stress on the SIAD zygapophysial joints was less than that on NAD zygapophysial joints. Stresses on the NAD zygapophysial joints were higher than those on SIAD and physiological discs during rotation. The stress on the SIAD zygapophysial joints was not significantly different from that on physiological discs during rotation. For SIADs and NADs, the stresses on the zygapophysial joints and the displacements of the discs were greater compared with those of the physiological discs during extension. The SIADs affected the variations in the stresses on the implanted segment more than the NADs, and the SIADs protected the zygapophysial joints of the implanted segment to a higher degree than the NADs.

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Bioinspired Intervertebral Disc with Multidirectional Stiffness Prepared via Multimaterial Additive Manufacturing

Song

Qian

Liu

et al. 2023

Adv Funct Materials

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Degenerative disc disease (DDD) has become a significant public health issue worldwide. This can result in loss of spinal function affecting patient health and quality of life. Artificial total disc replacement (A‐TDR) is an effective approach for treating symptomatic DDD that compensates for lost functionality and helps patients perform daily activities. However, because current A‐TDR devices lack the unique structure and material characteristics of natural intervertebral discs (IVDs), they fail to replicate the multidirectional stiffness needed to match physiological motions and characterize anisotropic behavior. It is still unclear how the multidirectional stiffness of the disc is affected by structural parameters and material characteristics. Herein, a bioinspired intervertebral disc (BIVD‐L) based on a representative human lumbar segment is developed. The proposed BIVD‐L reproduces the multidirectional stiffness needed for the most common physiological kinematic behaviors. The results demonstrate that the multidirectional stiffness of the BIVD‐L can be regulated by structural and material parameters. The results of this research deepen knowledge of the biomechanical behavior of the human lumbar disc and may provide new inspirations for the design and fabrication of A‐TDR devices for both engineering and functional applications.

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An in vitro biomechanical comparison of Cadisc™-L with natural lumbar discs in axial compression and sagittal flexion

Cited by 18 publications

References 23 publications

Finite element analysis of fibre-reinforced constitutive formulation of Cadisc-L

Finite element analysis of fibre-reinforced constitutive formulation of Cadisc-L

Biomechanical effects of semi-constrained integrated artificial discs on zygapophysial joints of implanted lumbar segments

Bioinspired Intervertebral Disc with Multidirectional Stiffness Prepared via Multimaterial Additive Manufacturing

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