An Immunological Study of Pasteurella Septica

Roberts, RM

doi:10.1016/s0368-1742(47)80032-3

Cited by 65 publications

(6 citation statements)

References 11 publications

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“…Pasteurella multocida is one source of systemic and respiratory disease in a variety of domestic and feral animals. Several schemes have been developed for serologic classification and epidemiologic study of the organism (1,3,7,11,12,14). These schemes have included specific agglutination, passive hemagglutination (PHA), passive protection of mice, and gel diffusion precipitin (GDP) tests.…”

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confidence: 99%

“…The PHA test for identification of specific capsule antigen (1) and the GDP test for identification of specific somatic antigen (7) are currently in prominent use. The mouse passive protection test (14), which correlates with the PHA test (4), is sometimes used for identification of specific capsule antigen in areas where hemorrhagic septicemia of cattle and buffalo is endemic, i.e., in Africa and Asia. Four specific capsule serogroups (A, B, D, and E) are recognized by the PHA test, and 16 specific somatic serotypes (1 through 16) are recognized by the GDP test.…”

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confidence: 99%

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Serogroup F, a new capsule serogroup of Pasteurella multocida

Rimler¹,

Rhoades²

1987

J Clin Microbiol

125

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Four capsule serogroups (A, B, D, and E) have been described by using passive hemagglutination tests. Serogroups A and D predominate in pasteurelloses of avian species. A new capsule serogroup of Pasteurella multocida has been isolated from turkeys in Arkansas, California, Indiana, Iowa, Missouri, New Jersey, and Virginia. Strains belonging to the new serogroup were somatic serotype 1, 3, 7, or 12, and they varied in virulence for mice and poults. Antisera made in rabbits passively protected mice against challenge with the same serogroup regardless of somatic serotype.

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confidence: 99%

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confidence: 99%

Serogroup F, a new capsule serogroup of Pasteurella multocida

Rimler¹,

Rhoades²

1987

J Clin Microbiol

125

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“…The mouse has been used in passive protection tests with Pasteurella multocida as (i) a method of typing organisms (8) and (ii) for defining the protective antibody response of cattle and buffalo to vaccination (1,3,4; Ramdani, unpubl. data).…”

Section: Introductionmentioning

confidence: 99%

Pasteurella multocida infections in mice with reference to haemorrhagic septicaemia in cattle and buffalo

Ramdani

Dawkins

Johnson

et al. 1990

Immunology & Cell Biology

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Summary Haemorrhagic septicaemia (HS) is an infectious disease of cattle and buffalo caused by particular serotypes of Pasteurella multocida and is one ofthe most economically important livestock diseases in South-East Asia. While HS has been recognized for many years, very little is understood about the disease, primarily because ofthe expense of cattle and a lack of suitable animal models. The suitability of using mice to study HS was assessed using parameters such as the critical pathogenic dose, kinetics of infection, pathology of disease and resistance to reinfection. Pasteurella multocida Ml404. the type strain for Carter group B, the serotype responsible for Asian HS. was injected intraperitoneally into BALB/c mice. As few as 20 colony forming units produced an overwhelming septicaemia in mice in less than 30 h. The kinetics of infection demonstrated a very rapid in viva multiplication rate. There was no evidence of inhibition of bacterial cell growth by natural host defence mechanisms, even with the very small inocula used. The gross pathology ofthe disease in mice was characterized by splenomegaly, lymphadenopathy and petechial haemorrhages similar to that observed in cattle and buffalo with HS. Mice were found to develop a short-lived resistance to reinfection following a primary infection which had been successfully treated with antibiotics. The mouse would seem to provide an ideal tool by which to study HS. but warrant further studies in order to be able to critically assess it as a model for this economically important disease.

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“…The first clear evidence that different immunotypes of P. multocida could cause fowl cholera was obtained by Roberts (11) in mouse-protection tests. He found that at least three immunotypes occurred.…”

Section: Introductionmentioning

confidence: 99%

Simplified Identification of Somatic Varieties of Pasteurella multocida Causing Fowl Cholera

Gr¹

1972

Avian Diseases

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Representative type strains as well as field strains of Pasteurella multocida from fowl cholera were examined by the indirect hemagglutination procedure and by a rapid plate agglutination test. The former method identified the specific capsular or K substance, and the latter identified the somatic antigens. Inagglutinable organisms were made agglutinable for the rapid procedure by treatment with hyaluronidase. The results confirmed the identity of representative type strains. Of the 25 field strains examined, one was identified as a type D of low pathogenicity, and the other 25 were type A: 19 serotype 8:A (Heddleston type 3), 3 serotype 5:A (Heddleston type 1), 2 Heddleston's type 4, and 1 serotype 1:A.

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An Immunological Study of Pasteurella Septica

Cited by 65 publications

References 11 publications

Serogroup F, a new capsule serogroup of Pasteurella multocida

Serogroup F, a new capsule serogroup of Pasteurella multocida

Pasteurella multocida infections in mice with reference to haemorrhagic septicaemia in cattle and buffalo

Simplified Identification of Somatic Varieties of Pasteurella multocida Causing Fowl Cholera

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