An immunohistochemical study of the Mueller cells of the chicken retina.

Ikeda, Akira; Yoshii, Itaru; Mishima, Noboru

doi:10.1679/aohc1950.43.175

Cited by 11 publications

(3 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…More recently, viral labeling studies were carried out in rat embryos to show that Müller cells arise from a single progenitor cell that gives rise to rod and bipolar neurons (Turner and Cepko, ; Giannelli et al, ). Some investigators have speculated that Müller cells are derived from glioblasts (Ikeda et al, ), and in vitro differentiation studies suggest that glioblasts are derived from neuroepithelium (Kessaris et al, ), but no studies have conclusively demonstrated this in vivo . Thus, despite considerable investigation and speculation, the embryonic origin(s) of Müller glia remain unknown.…”

Section: Contribution Of Neural Crest Cells To Retinal Regenerationmentioning

confidence: 99%

The capacity of neural crest‐derived stem cells for ocular repair

Liu

Hunter

Smith

et al. 2014

Birth Defects Research Pt C

View full text Add to dashboard Cite

Whether it is due to a particular epigenetic signature, or some other component of an embryonic differentiation program, accumulating evidence indicates that the origins of a stem cell has a profound impact on the potential of a tissue to regenerate and repair. Here, we focus on Müller glia, long considered the stem cells of the retina, and their surprising derivation from the neural crest. Whether the multipotent properties of a subset of Müller glia is associated with their neural crest origin remains a tantalizing possibility.

show abstract

Section: Contribution Of Neural Crest Cells To Retinal Regenerationmentioning

confidence: 99%

The capacity of neural crest‐derived stem cells for ocular repair

Liu

Hunter

Smith

et al. 2014

Birth Defects Research Pt C

View full text Add to dashboard Cite

show abstract

“…This staining has been exploited to characterize morphologically astrocytes (Bjorklund et al, 1985;Hajos and Kalman, in press;Kalman and Hajos, in press), to decide upon the astrocytic nature of some ambiguous cell types Bignami, 1984;de Vitry et al, 1981;Ikeda et al, 1980;Jesse and Mirsky, 1983;Suess and Pilska, 19811, to describe CNS areas of regular glial organization , to investigate the role of astroglia in brain development (Choi and Lapham, 1978;Woodhams et al, 1981), to demonstrate astroglial growth around neural tissue grafts (Azmitia and Whitaker, 1983;Bjorklund and Dahl, 1982;Bjorklund et al, 1984), and it proved to be of diagnostic value in pathological states accompanied by reactive gliosis (Bignami and Dahl, 1976;Bignami et al, 1980;Goebel et al, 1987;Vacca and Nelson, 1981;Vacca-Galloway, 1986). …”

Section: Introductionmentioning

confidence: 99%

Remote astrocytic response as demonstrated by glial fibrillary acidic protein immunohistochemistry in the visual cortex of dorsal lateral geniculate nucleus lesioned rats

Hajós

Kálmán

Zilles

et al. 1990

Glia

View full text Add to dashboard Cite

The reaction of astroglia was investigated after unilateral destruction of the dorsal lateral geniculate nucleus in the primary visual cortex of adult albino rats. The destruction of the dorsal lateral geniculate nucleus was performed by stereotaxic injections of ibotenic acid, and the location was verified in Nissl stained sections in each animal. Electron microscopic observations demonstrated the presence of degenerating axon terminals surrounded by hypertrophic astroglial processes mainly in layers III and IV of the ipsilateral primary visual cortex. The ipsilateral (impaired) and contralateral (control) sides of the primary visual cortex showed light microscopically a clearly differing appearance and distribution of glial fibrillary acidic protein (GFAP) immunoreactivity 7 to 11 days after the unilateral injection of ibotenic acid into the dorsal lateral geniculate nucleus. Whereas the control side of the primary visual cortex showed GFAP staining only in the subpial zone of layer I and close to the white matter, all layers of the impaired cortex showed an intense GFAP immunoreactivity. The increase in immunoreactivity was confined to the primary visual cortex. The extent of and increase in immunoreactivity was corroborated by image analysis. These findings were interpreted as a localized hypertrophy of astroglia caused by the anterograde degeneration of geniculocortical terminals. This hypertrophy is accompanied by an increase in GFAP, which may represent the stabilization of the cytoskeleton of newly formed glial processes involved in the rearrangement of the impaired neuropil.

show abstract

“…The structural and functional differentiation of the chick Mü ller cell has been investigated (Coulombre, 1955;Meller and Glees, 1965;Morris and Moscona, 1970;Uga and Smelser, 1973;Meller and Tetzlaff, 1976;Ikeda et al, 1980;Moscona and Linser, 1983;Moscona, 1983;Prada et al, 1989bPrada et al, , 1995Prada et al, , 1998Schlosshauer et al, 1991;Willbold et al, 1995). The Golgi studies by Prada et al (1989bPrada et al ( , 1998 showed the prenatal development of its shapes.…”

mentioning

confidence: 99%

Shape diversity among chick retina Müller cells and their postnatal differentiation

Anezary

Medina

Sánchez-Nogueiro

et al. 2001

J of Comparative Neurology

View full text Add to dashboard Cite

It is currently believed that in each vertebrate species Müller cells in the central retina constitutes a fairly homogeneous population from the morphologic point of view and that particularly the chick Müller cell attains full shape differentiation at prenatal stages. However, in this study of the chick retina, from day 1 to day 55 of life, we show that there is a large variety of Müller cell shapes and that many of them complete shape differentiation postnatally. We used a cell dissociation method that preserves the whole shape of the Müller cells. Unstained living and unstained fixed cells were studied by phase-contrast microscopy, and fixed cells immunostained for intermediate filaments of the cytoskeleton were studied by fluorescence microscopy. Our results show that (1) Müller cell shapes vary in the origination of the hair of vitread processes, in the shape of the ventricular (outer or apical) process, in the presence or absence of an accessory process, as well as in the number and shape of processes leaving from the ventricular process at the level of the outer nuclear and outer plexiform layers (ONL/OPL); (2) during the first month of life, many Müller cells differentiate the portion of the ventricular process that traverses the ONL, most Müller cells differentiate the ONL/OPL processes, and all Müller cells differentiate the thin short lateral processes leaving from the vitread hair processes at the level of the inner plexiform layer (IPL). The number of cells differing in the shape of the ventricular process and that of cells with and without accessory process were estimated. The spatial relationship between the outer portion of the ventricular process of the Müller cell and the photoreceptor cells was also studied. Our results show that the branching of the ventricular process and the refinement of Müller cell shape is achieved without apparent participation of growth cones. We give a schematic view of how the branching of the ventricular process might take place and propose the size increase of photoreceptor soma as a factor responsible for this branching.

show abstract

An immunohistochemical study of the Mueller cells of the chicken retina.

Cited by 11 publications

References 15 publications

The capacity of neural crest‐derived stem cells for ocular repair

The capacity of neural crest‐derived stem cells for ocular repair

Remote astrocytic response as demonstrated by glial fibrillary acidic protein immunohistochemistry in the visual cortex of dorsal lateral geniculate nucleus lesioned rats

Shape diversity among chick retina Müller cells and their postnatal differentiation

Contact Info

Product

Resources

About