An experimental system for a heterotopic pain stimulation study in humans

Motohashi, Katsunori; Umino, Masahiro; Fujii, Yoshiko

doi:10.1016/s1385-299x(02)00179-4

Cited by 13 publications

(21 citation statements)

References 37 publications

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“…The method of electrical tooth stimulation has been described in previous reports (Umino et al, 1996;Motohashi and Umino, 2001;Motohashi et al, 2002;Fujii et al, 2006;Oono et al, 2008). A vital, unfilled upper right central incisor was stimulated, and cotton rolls were inserted above the tooth to isolate it from…”

Section: Electrical Tooth Stimulationmentioning

confidence: 99%

Effects of dexmedetomidine on conditioned pain modulation in humans

Baba

Kohase

Oono

et al. 2012

European Journal of Pain

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Section: Electrical Tooth Stimulationmentioning

confidence: 99%

Effects of dexmedetomidine on conditioned pain modulation in humans

Baba

Kohase

Oono

et al. 2012

European Journal of Pain

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“…The system consists of an electrical tooth stimulation unit for application of the test stimulation and an SEP recording unit to objectively estimate pain. We previously reported the occurrence of DNIC effects in the trigeminal nerve territory using this experimental system in humans (Motohashi and Umino, 2001; Motohashi et al, 2002).…”

Section: Dnic Studymentioning

confidence: 99%

“…The SEP recordings were performed according to a previously described method (Umino et al, 1995;Motohashi and Umino, 2001;Motohashi et al, 2002). Evoked potentials were recorded by Ag/Ag-Cl electrodes according to the international 10-20 system at Cz (verex) in reference to the earlobe contralateral to the site of stimulation.…”

Section: Recording Of Tooth Evoked Potentialsmentioning

confidence: 99%

Heterotopic ischemic pain attenuates somatosensory evoked potentials induced by electrical tooth stimulation: Diffuse noxious inhibitory controls in the trigeminal nerve territory

Fujii

Motohashi

Umino

2006

European Journal of Pain

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The purpose of this study was to determine whether the late component of somatosensory evoked potentials (SEP) induced by electrical tooth stimulation and pain intensity are inhibited by heterotopic ischemic stimulation. The tourniquet pressure with 50 mmHg greater than the individual's systolic pressure was applied to the left upper arm for 10 min as ischemic conditioning stimulation. The late component of SEP and visual analogue scale (VAS) were recorded at 4 times and both were significantly decreased when ischemic conditioning stimulation was applied. The maximum reductions in SEP amplitude and the VAS value were 26.1% and 21.2%, respectively, during ischemic conditioning stimulation. After-effect was observed 5 min after removal of the conditioning stimulation. The present study revealed that heterotopic ischemic stimulation attenuated the late component of SEP induced by electrical tooth stimulation, triggering diffuse noxious inhibitory controls (DNIC) and after-effects in the trigeminal nerve territory. It was also suggested that the DNIC effect differs, depending on the intensity, kind, and quality of the test and conditioning stimuli.

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“…This aftereffect is a conceivably major feature in DNIC and could persist for several minutes as long‐lasting poststimulus effects [2,3,9,18]. DNIC was effective on both unmyelinated and myelinated fibers, but it was much more effective on the former [19,20].…”

Section: Introductionmentioning

confidence: 99%