An experimental study of magnetic compression technique for ureterovesical anastomosis in rabbits

Abstract

This study aimed to explore the feasibility of the magnetic compression technique (MCT) for ureterovesical anastomosis in a rabbit model with ureteral obstruction. The distal ureteral obstruction model using female New Zealand rabbits was induced by ligating the distal end of the right ureter with silk thread for four weeks. A pair of cylindrical NdFeB magnets (daughter magnet and parent magnet) with a hole in the center was used for the ureterovesical anastomosis. The daughter magnet and the parent magnet were respectively placed close to the obstruction site through the dilated proximal ureter and urethra, and then the daughter-parent magnets pair was attracted together automatically. Postoperative X-rays were taken to confirm the position of the magnets. The anastomotic stoma specimens were obtained two weeks postoperatively, and the anastomotic stoma formation was observed by the naked eye and histological staining. The operation time and the anastomotic burst pressure were measured. The ureter was significantly dilated in the fourth week after ligation, which satisfied the placement of the daughter magnet. The ureterovesical magnet placements were successfully performed in ten experimental rabbits, with an operation time of 36.5 ± 6.09 min. The parent and daughter magnets attracted each other well and were subsequently removed through the urethra two weeks postoperatively, resulting in the establishment of ureterovesical anastomosis. The anastomotic burst pressure was 147.5 ± 14.59 mmHg. Gross specimens and histological examination of the anastomotic stoma showed that the anastomotic stoma healed well. MCT is feasible and simple for ureterovesical anastomosis.

Maximizing the extraction yield of plant gum exudate using response surface methodology and artificial neural networking and pharmacological characterization

“…Collected organs were weighted and preserved in 10 % v/v solution. Tissues were cut to prepare slides which were observed under microscope 23,24 .…”

Maximizing the extraction yield of plant gum exudate using response surface methodology and artificial neural networking and pharmacological characterization

“…Collected organs were weighted and preserved in 10% v/v solution. Tissues were cut to prepare slides which were observed under microscope 24,25 .…”

Influence of different magnetic forces on the effect of colonic anastomosis in rats

“…The research on MCA and its clinical application in gastroenterology comprises esophageal[ 1 - 3 ], gastrointestinal[ 4 - 6 ], and small bowel[ 7 - 9 ] anastomosis. Other examples include vascular[ 10 - 11 ] and ureterovesical[ 12 ] anastomosis. During MCA of the digestive tract, the pathological process is ischemia-necrosis-shedding in the compressed tissues between the magnets and adherence-repair-healing in the surrounding tissues[ 13 ].…”