An exophytic hepatic metastasis of mucinous colon cancer

Nagata, Hiroshi; Hayashi, Ken; Mike, Makio

doi:10.1093/jjco/hyv059

Cited by 5 publications

(5 citation statements)

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“…The accuracy of preoperative MRI in determining the presence of mucin in a CRCLM appears to be limited based on the data available from our study, with a sensitivity of 31.3% when the radiologist is blinded to the histological subtype. While there are some publications documenting the features of mucinous CRCLM on different imaging modalities, there appears to be a paucity of data on the performance of MRI at detecting the presence of mucin in CRCLM (24,(30)(31)(32). There is a single study that demonstrates a sensitivity of 56% when a combination of MRI and PET are used to try and detect mucin in CRCLM, clearly the routine use of PET to determine the presence of mucin cannot be recommended with a sensitivity of only 56%.…”

Section: Discussionmentioning

confidence: 99%

An Analysis of Clinicopathological Outcomes and the Utility of Preoperative MRI for Patients Undergoing Resection of Mucinous and Non-Mucinous Colorectal Cancer Liver Metastases

et al. 2022

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Background and AimsMucinous colorectal cancer has traditionally been associated with high rates of recurrence and poor long-term survival. There is limited published data on outcomes for patients undergoing liver resection for metastatic mucinous colorectal cancer. The aim of this study was to compare the clinicopathological outcomes for patients with mucinous colorectal cancer liver metastases (CRCLM) undergoing liver resection to a matched group of patients with adenocarcinoma not otherwise specified (NOS) and to evaluate the accurary of preoperative magnetic resonance imaging (MRI) at detecting the presence of mucin in liver metastases.Materials and MethodsPatients with mucinous CRCLM undergoing liver resection were matched 1:3 to patients with adenocarcinoma NOS CRCLM. Clinicopathological data from the primary tumour and metastatic lesion were collected and compared between the groups. Hepatic recurrence-free, disease-free and overall survival were compared between the groups. The ability of preoperative MRI to detect mucin in CRCLM was also evaluated.ResultsA total of 25 patients with mucinous CRCLM underwent surgery over the 12-year period and were matched to 75 patients with adenocarcinoma NOS. Clinicopathological findings were similar between the groups. Resection of mucinous CRCLM was feasible and safe with similar levels of morbidity to adenocarcinoma NOS. There were no differences identified in hepatic recurrence-free (p=0.85), disease-free (p=0.25) and overall survival (p=0.98) between the groups. MRI had a sensitivity of 31.3% in detecting the presence of mucin in CRCLM.ConclusionPatients with mucinous CRCLM in this study had similar outcomes to patients with adenocarcinoma NOS. Based on our findings, histological subtype should not be taken into account when deciding on resectability of CRCLM.

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Section: Discussionmentioning

confidence: 99%

An Analysis of Clinicopathological Outcomes and the Utility of Preoperative MRI for Patients Undergoing Resection of Mucinous and Non-Mucinous Colorectal Cancer Liver Metastases

et al. 2022

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“…Several studies have described the imaging features of metastatic mucinous adenocarcinomas of the liver by using various imaging modalities. [5][6][7]16,17 Metastatic mucinous adenocarcinomas of the liver frequently show hypoechoic or anechoic echogenicity on ultrasonography, liquid attenuation on CT, and bright SI on T 2 weighted MR images that is similar to the SI of the cerebrospinal fluid, with rim enhancement, internal septa, or mural nodules after contrast enhancement. 6,16,17 In contrast, hepatic metastases from colorectal adenocarcinomas other than mucinous adenocarcinomas usually show a moderately high SI on T 2 weighted images.…”

Section: Discussionmentioning

confidence: 99%

“…[5][6][7]16,17 Metastatic mucinous adenocarcinomas of the liver frequently show hypoechoic or anechoic echogenicity on ultrasonography, liquid attenuation on CT, and bright SI on T 2 weighted MR images that is similar to the SI of the cerebrospinal fluid, with rim enhancement, internal septa, or mural nodules after contrast enhancement. 6,16,17 In contrast, hepatic metastases from colorectal adenocarcinomas other than mucinous adenocarcinomas usually show a moderately high SI on T 2 weighted images. 5,18 Because metastatic mucinous adenocarcinomas of the liver may show bright SI on T 2 weighted MR images due to abundant mucin production from the tumor, 16 metastatic mucinous adenocarcinomas of the liver may be difficult to differentiate from simple cysts of the liver when the former have no enhancing solid portions or mural nodules.…”

Section: Discussionmentioning

confidence: 99%

Differentiating metastatic mucinous colorectal adenocarcinomas from simple cysts of the liver using contrast-enhanced and diffusion-weighted MRI

Lee

Kim

Lee

et al. 2018

BJR

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“…Exophytic patterns of liver tumours were previously described for liver haemangioma (12), adenoma (13), focal nodular hyperplasia (10,14,15), angiomyolipoma (16), solitary fibrous tumour (17), hepatocellular carcinoma (18), cholangiocarcinoma (19) and metastases (20).…”

Section: Discussion Discussionmentioning

confidence: 99%

Pedunculated Focal Nodular Hyperplasia of the Liver

Martiniuc¹,

Dumitraşcu²

2018

SGO

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Focal nodular hyperplasia (FNH) is the second most common type of benign liver tumour, and it is more frequently encountered in young women and the right hemi-liver. Most patients are asymptomatic, and there is no malignant potential. Thus, the current guidelines do not recommend any treatment for uncomplicated FNH, and surgery is indicated only for some atypical patients (with complications or uncertain diagnosis). Pedunculated forms are atypical, rare features of FNH and appear to be more frequently associated with complications. We hereby report the case of a 40-year-old woman diagnosed at computed tomography with a lobulated subhepatic FNH with a long pedicle originating from segment III of the liver, which was successfully resected. Pedunculated FNH is associated with a challenging diagnosis and may require resection in order to avert potential complications such as compression of surrounding organs or torsion of the pedicle.

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An exophytic hepatic metastasis of mucinous colon cancer

Cited by 5 publications

References 0 publications

An Analysis of Clinicopathological Outcomes and the Utility of Preoperative MRI for Patients Undergoing Resection of Mucinous and Non-Mucinous Colorectal Cancer Liver Metastases

An Analysis of Clinicopathological Outcomes and the Utility of Preoperative MRI for Patients Undergoing Resection of Mucinous and Non-Mucinous Colorectal Cancer Liver Metastases

Differentiating metastatic mucinous colorectal adenocarcinomas from simple cysts of the liver using contrast-enhanced and diffusion-weighted MRI

Pedunculated Focal Nodular Hyperplasia of the Liver

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