An excised patch membrane sensor for arachidonic acid released in mouse hippocampal slices under stimulation of l-glutamate

Saitoh, Hiroto; Namatame, Yuko; Hirano, Atsushi; Sugawara, Masao

doi:10.1016/j.ab.2004.03.060

Cited by 9 publications

(2 citation statements)

References 45 publications

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“…3, we can identify very interesting connections between the identified genes and molecules such as Lactose and Galactose, that can be easily sensed with assessed nanotechnology. With respect to molecules that act as substrates for the P450 proteins family [36] (see Table 2 for a partial list), we can observe that the ones identified in this study (highlighted in bold) have already been sensed with this approach, and namely: caffeine [37], arachidonic acid [38], arachidonate [39], and linoleic acid [40].…”

Section: Resultsmentioning

confidence: 99%

Biochips for Regenerative Medicine: Real-time Stem Cell Continuous Monitoring as Inferred by High-Throughput Gene Analysis

et al. 2011

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Regenerative medicine is a novel clinical branch aiming at the cure of diseases by replacement of damaged tissues. The crucial use of stem cells makes this area rich of challenges, given the poorly understood mechanisms of differentiation. One highly needed and yet unavailable technology should allow us to monitor L. Zhu and G. del Vecchio contributed equally to this work. Electronic supplementary materialThe online version of this article

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Section: Resultsmentioning

confidence: 99%

Biochips for Regenerative Medicine: Real-time Stem Cell Continuous Monitoring as Inferred by High-Throughput Gene Analysis

et al. 2011

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“…An increase in AA promotes the subsequent production of HETEs and EETs along with other eicosanoids and the generation of ROS (82,146). The activation of PLA2 after ischemia is, in part, attributed to increased glutamate release from neuronal cells (136), which has also been shown to stimulate AA release in mouse hippocampal slices and cultured mouse brain astrocytes (150,164).…”

Section: Ischemic Strokementioning

confidence: 99%

P450 Eicosanoids and Reactive Oxygen Species Interplay in Brain Injury and Neuroprotection

Liu

Davis²,

Alkayed³

2018

Antioxidants & Redox Signaling

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EETs and HETEs exert their actions on brain cells by targeting multiple mechanisms, which include surface G-protein coupled receptors. The identification of high-affinity receptors for EETs and HETEs and their cellular localization in the brain will be a breakthrough in our understanding of these eicosanoids as mediators of cell-cell communications and contributors to brain development, function, and disease. Antioxid. Redox Signal. 00, 000-000.

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Transmembrane Signaling with Lipid‐Bilayer Assemblies as a Platform for Channel‐Based Biosensing

Sugawara

2017

The Chemical Record

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Artificial and natural lipid membranes that elicit transmembrane signaling is are useful as a platform for channel-based biosensing. In this account we summarize our research on the design of transmembrane signaling associated with lipid bilayer membranes containing nanopore-forming compounds. Channel-forming compounds, such as receptor ion-channels, channel-forming peptides and synthetic channels, are embedded in planar and spherical bilayer lipid membranes to develop highly sensitive and selective biosensing methods for a variety of analytes. The membrane-bound receptor approach is useful for introducing receptor sites on both planar and spherical bilayer lipid membranes. Natural receptors in biomembranes are also used for designing of biosensing methods.

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An excised patch membrane sensor for arachidonic acid released in mouse hippocampal slices under stimulation of l-glutamate

Cited by 9 publications

References 45 publications

Biochips for Regenerative Medicine: Real-time Stem Cell Continuous Monitoring as Inferred by High-Throughput Gene Analysis

Biochips for Regenerative Medicine: Real-time Stem Cell Continuous Monitoring as Inferred by High-Throughput Gene Analysis

P450 Eicosanoids and Reactive Oxygen Species Interplay in Brain Injury and Neuroprotection

Transmembrane Signaling with Lipid‐Bilayer Assemblies as a Platform for Channel‐Based Biosensing

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