An Evaluation of the Antimicrobial Activity of Commiphora myrrha Nees (Engl.) Oleo-gum Resins from Saudi Arabia

Abstract

The present work was aimed to evaluate oleo-gum resins aqueous, methanol and chloroform extracts of Commiphora myrrha for antimicrobial activity against four types of bacteria and twelve species and strains of fungi. All of the oleo-gum resin extracts irrespective of their types inhibited the growth of all microbes to varying degrees. Aqueous extract showed the least antibacterial and antifungal activity against all of the pathogens used especially with regard to gram positive bacteria Staphylococcus aureus (11 mm) and Escherichia coli (11 mm) in concentration of 100 mg mLG 1 as compared to methanol or chloroform. Less or no activity was observed against Trichophyton concentricum (7.01 mm) and 4.01 mm inhibition zone for Candida rugosa in the same concentration used. The oleo-gum resins methanol extracts in different concentrations were significantly inhibitory to the growth of the different tested fungal dermatophytes. Reduction in mycelial weight of fungi was directly correlated with concentration of extract. The concentration of 200 mg mLG 1 of myrrha was the most inhibitory against Epidermophyton floccosum with 2 g mycelial fresh weight while the less inhibition in the growth was obtained in Candida albicans and it was 6.61 g in the same extract concentration. The other used fungal or bacterial groups showed varying degrees of activity pending on the type of extract used. The Minimum Inhibitory Concentration (MIC) values of methanol and aqueous extracts of oleo-gum resins of myrrh showed that the highest values were obtained in methanol extract for Trichophyton concentricum and lowest MIC values for the same extract for the bacterium Staphylococcus aureus. In the aqueous extract of myrrha the highest and lowest MIC values were found for Bacillus subtilis and Pseudomonas aeruginosa. Phytochemical analyses showed the presence of Sesquiterpenes (Isoprenoids i.e., Terpenoids) and Furanosesquiterpenes as major constituents of the oleo-gum resins of the plant. These results confirm the antibacterial and antifungal activity of gum resins and support the traditional use of the myrrh in therapy of bacterial infections.

In vitro estimation of superfluid critical extracts of some plants for their antimicrobial potential, phytochemistry, and GC–MS analyses

“…Also, the current results of myrrh are compatible with those who recorded the presence of terpenoids, steroids, tannins, volatile oils, and resins [ 47 ].…”

Bioactive Potential of 3D-Printed Oleo-Gum-Resin Disks:B. papyrifera,C. myrrha, andS. benzoinLoading Nanooxides—TiO2, P25, Cu2O, and MoO3

“…The results from Table 1 show that the bioactivity of plant resins in pure state was effective and the addition of 10% w.t of oxides nanoparticles increased the efficiency of materials, as expected. Regarding the resin of C. myrrha , the antibiogram of bacteria and fungus under test corroborates the results obtained by Omer et al [ 80 ] and in Alhussaini et al [ 81 ]; concerning the resin of B. papyrifera , the results present in this study are in accordance with Camarda et al [ 25 ], Abdallah et al [ 82 ], Abdalah and Khalid [ 83 ], and de Rapper et al [ 84 ]; and in relation to the resin of S. benzoin the results showed here are in accordance with the findings previously obtained by Dahni et al [ 85 ] and De Rapper et al [ 86 ].…”

In Vitro Evaluation of Antimicrobial potential of Some Medicinal Plants Extracted by Supercritical Fluid Extractor; Their Phytochemistry and GC-MS Analyses

“…Also, the current results of myrrh are compatible with those who recorded the presence of terpenoids, steroids, tannins, volatile oils and resins [41].…”