An epidemiological study of congenital malformations in new born

Abstract

In a prospective study of 3000 consecutive deliveries (14 twin deliveries), the rate of congenital malformation was reported to be 27.20 per 1000 births (82 out of 3014). No significant difference was observed in the frequency of congenital malformation in urban rural status, in different religion and caste, and in male female babies. An increase in frequency was seen in advanced maternal age and in primi and fourth gravida mothers. A number of environmental factors studied, such as use of different tooth powders, type of drinking water, different cooking vessels, associated vitamin deficiencies did not seem to influence the prevalence of birth defects significantly. The factors which significantly increased the rate of congenital malformation were consanguinity in parents, heredofamilial history of malformations, presence of hydramnios, maternal febrile illness in first trimester, past history of abortion and history of progesterone intake during pregnancy.

Study of Congenital Malformations in a Tertiary Care Centre, Government General Hospital, Kakinada

“…In our study, incidence of congenital anomaly was 0.7% which is similar to the figure (0.69%) observed by Taboo ZAA, [5] but Chinara PK and Singh S, [6] Chaturvedi P and Banerjee KS [7] reported 2.08% and 2.27% respectively. This variation may be due to different geographical area, social factor and racial difference.…”

Profile of gross congenital malformations among live newborns and its associated risk factors from a tertiary care rural teaching institute

“…7 The incidence of congenital malformations in our study was found to be 1.7 per 1000 live births which is consistent with studies conducted in various parts of our country. 1,[8][9][10][11][12][13][14] The reported incidence in various studies is around 2% except the study conducted by Marwah et al who have reported a higher incidence of malformations (4.44%) in Punjab. 15 This could be due to increasing number of referrals coming to the hospital, inclusion of minor anomalies, racial, geographic and ethnic factors.…”

Congenital malformations in Assam

“…In a study performed at Wardha, India, the incidence of congenital malformation was found to be 2.72%. [8] An increase in frequency was seen in advanced maternal age and in primi and fourth gravida mothers. Outside India, the incidence varied from 0.9% in Northampton Shire[9] to 3.4% in Michigan[10] and 5.5% in Afghanistan.…”