An epidemiological evaluation of Mycobacterium bovis infections in wild game animals of the Spanish Mediterranean ecosystem

Parra, Augusto; García, Alfredo; Inglis, Neil F.; Tato, A.; Alonso, J.M.; Mendoza, M. Hermoso de; Mendoza, J. Hermoso de; Larrasa, J.

doi:10.1016/j.rvsc.2005.05.010

Cited by 61 publications

(59 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It was also found in the www.mbovis.org database as SB0265. This pattern was reported in isolates from wild boar, red deer, and cattle from Extremadura, western Spain (Parra et al, 2005). This region is contiguous to the south and west with study areas B and C. The unique isolate (our designation ID-80) was not found in any database.…”

Section: Resultssupporting

confidence: 59%

“…At study area G, located in the foothills of Sierra Morena, our estimated M. bovis infection rate was similar (46%). In contrast, Parra et al (2006) reported a 2.3% TBL prevalence rate in wild boar in the Spanish region of Extremadura. This value is lower than the M. bovis infection rate we estimated in nearby study areas B and C (12% for both areas combined; CI P95% 55-24%).…”

Section: Discussionmentioning

confidence: 82%

“…This value is lower than the M. bovis infection rate we estimated in nearby study areas B and C (12% for both areas combined; CI P95% 55-24%). Although this difference in prevalence may be real, it may as well be the result of 1) the use of different diagnostic approaches (bacterial culture vs. gross pathology), 2) the use of different study designs (targeted surveys vs. official veterinary inspection of hunted animals), or 3) the lapse in time between the two studies; the study by Parra et al (2006) was performed in 2002 and the authors suggested that the disease incidence was increasing.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Epidemiology of Mycobacterium Bovis Infection in Wild Boar (Sus Scrofa) From Portugal

Santos

Correia-Neves

Ghebremichael

et al. 2009

Journal of Wildlife Diseases

View full text Add to dashboard Cite

ABSTRACT:Tuberculosis has been diagnosed in wild boar (Sus scrofa) in several European countries during the last decade; however, almost no information has been reported to date for Portugal. This study aimed to investigate tuberculosis in wild boar in Portugal through characterization of Mycobacterium bovis infection and identification of disease risk factors. Tissue samples were obtained from hunted wild boar during the 2005 and 2006 hunting seasons. Samples were inspected for gross lesions and processed for culture. Acid-fast bacterial isolates were identified by polymerase chain reaction and spoligotyping. Associations between tuberculosis in wild boar and several variables linked to wild ungulate diversity and relative abundance, livestock density, and cattle tuberculosis incidence were investigated. Mycobacterium bovis isolates were identified in 18 of 162 wild boars from three of eight study areas. Infection rates ranged from 6% (95% confidence interval [CI P95% ]51-21%) to 46% (CI P95% 527-67%) in the three infected study areas; females in our sample were at greater risk of being infected than males (odds ratio54.33; CI P95% 53.31-5.68). Spoligotyping grouped the M. bovis isolates in three clusters and one isolate was a novel spoligotype not previously reported in international databases. Detection of M. bovis was most consistently associated with variables linked to wild ungulate relative abundance, suggesting that these species, particularly the wild boar, might act as maintenance hosts in Portugal.

show abstract

Section: Resultssupporting

confidence: 59%

Section: Discussionmentioning

confidence: 82%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Epidemiology of Mycobacterium Bovis Infection in Wild Boar (Sus Scrofa) From Portugal

Santos

Correia-Neves

Ghebremichael

et al. 2009

Journal of Wildlife Diseases

View full text Add to dashboard Cite

show abstract

“…They did not develop generalized lesions in the respiratory tract, which gave credence to the argument, although molecular typing showed that the same spoligotype affected both livestock and wild boar in Italy. Several recent publications from Spain demonstrate that intensively raised wild boars within the confines of fenced areas of wilderness can be a major source of bTB (Parra et al 2006;Vicente et al 2006). In the Mediterranean region of Spain, wild boar raised semiwild (with feeding and watering within fenced areas, so the pigs could be used as game animals by hunters) have created a unique epidemiological niche that has led to major disease outbreaks owing to M. bovis in the wildlife with potential exposure to domestic animals.…”

Section: Bacteria In Wild Boars That Are Potentially Transmissible Tomentioning

confidence: 99%

Wild boars as sources for infectious diseases in livestock and humans

Meng

Lindsay

Sriranganathan

2009

Phil. Trans. R. Soc. B

370

302

View full text Add to dashboard Cite

Wild boars (Sus scrofa) are indigenous in many countries in the world. These free-living swine are known reservoirs for a number of viruses, bacteria and parasites that are transmissible to domestic animals and humans. Changes of human habitation to suburban areas, increased use of lands for agricultural purposes, increased hunting activities and consumption of wild boar meat have increased the chances of exposure of wild boars to domestic animals and humans. Wild boars can act as reservoirs for many important infectious diseases in domestic animals, such as classical swine fever, brucellosis and trichinellosis, and in humans, diseases such as hepatitis E, tuberculosis, leptospirosis and trichinellosis. For examples, wild boars are reservoirs for hepatitis E virus, and cluster cases of hepatitis E have been reported in Japan of humans who consumed wild boar meat. In Canada, an outbreak of trichinellosis was linked to the consumption of wild boar meat. The incidence of tuberculosis owing to Mycobacterium bovis has increased in wild boars, thus posing a potential concern for infections in livestock and humans. It has also been documented that six hunters contracted Brucella suis infections from wild swine in Florida. This article discusses the prevalence and risk of infectious agents in wild boars and their potential transmission to livestock and humans.

show abstract

“…21 In contrast, members of the MAC are only sporadically detected. 2,23 Moreover, although most M. bovis-infected wild boar develop character-istic gross lesions, 20 infections with MAC species often cause only minimal pathology, if any. 11 Bacterial culture is the gold standard technique for diagnosing mycobacterial infections.…”

Section: Introductionmentioning

confidence: 99%

Serologic Tests for Detecting Antibodies against Mycobacterium Bovis and Mycobacterium Avium Subspecies Paratuberculosis in Eurasian Wild Boar (Sus Scrofa Scrofa)

et al. 2011

View full text Add to dashboard Cite

Abstract. New tools to detect exposure of free-range Eurasian wild boar (Sus scrofa scrofa) to pathogenic mycobacteria would be valuable for improved disease surveillance and wildlife management. Two hundred sera from wild boar of known Mycobacterium bovis infection status were used to evaluate test suitability for the detection of antibodies against M. bovis and Mycobacterium avium subsp. paratuberculosis (or crossreacting members of the M. avium complex). Two traditional enzyme-linked immunosorbent assays were evaluated using M. bovis purified protein derivative (bPPD) and paratuberculosis protoplasmatic antigen 3 (PPA3) as antigens, respectively, and a new point-of-care test format for bovine tuberculosis (bTB) that uses the innovative dual-path platform (DPP TB) test. The effect of individual factors (sex, age, lesions) on the diagnostic performance of the serologic tests was also determined. Although the DPP had a sensitivity of 89.6% and a specificity of 90.4%, for bPPD, the sensitivity was 79.2% and the specificity 100%. Both tests had a kappa agreement of 0.80. Sixty-five of 68 (95.6%) wild boar sera with antibodies against the PPA3 antigen corresponded to known M. bovis-infected wild boar. Significant differences were not observed in the bPPD and DPP readings among lesion categories or between age classes. A slight sex-related difference in sensitivity toward males in the DPP was found, but it was not detected in the bPPD enzyme-linked immunosorbent assay. The results support the use of antibody-based diagnostic tests for both large-scale and individual bTB testing of Eurasian wild boar and suggest that wild boar cannot be used as sentinels for infections caused by M. avium complex members.

show abstract

An epidemiological evaluation of Mycobacterium bovis infections in wild game animals of the Spanish Mediterranean ecosystem

Cited by 61 publications

References 26 publications

Epidemiology of Mycobacterium Bovis Infection in Wild Boar (Sus Scrofa) From Portugal

Epidemiology of Mycobacterium Bovis Infection in Wild Boar (Sus Scrofa) From Portugal

Wild boars as sources for infectious diseases in livestock and humans

Serologic Tests for Detecting Antibodies against Mycobacterium Bovis and Mycobacterium Avium Subspecies Paratuberculosis in Eurasian Wild Boar (Sus Scrofa Scrofa)

Contact Info

Product

Resources

About