An emotional Stroop functional MRI study of euthymic bipolar disorder

Malhi, Gin S; Lagopoulos, Jim; Sachdev, Perminder S.; Ivanovski, Belinda; Shnier, Ron

doi:10.1111/j.1399-5618.2005.00255.x

Cited by 169 publications

(157 citation statements)

References 84 publications

Supporting

Mentioning

130

Contrasting

Unclassified

Order By: Relevance

“…However, our findings are consistent with previous Stroop studies that reported reduced activation to conflict trials in IFG/MFG, medial SFG/SMA, parietal cortex, and basal ganglia in euthymic BD patients (Malhi et al, 2005;Strakowski et al, 2005;Kronhaus et al, 2006;Roth et al, 2006;Pompei et al, 2011). Stroop-like conflict has rarely been studied during affective episodes, but decreased activity in the IFG, together with hypoactivation of the basal ganglia, thalamus and/or parietal areas, was reported during inhibition and emotion categorization tasks in manic and depressed patients, as well as euthymic patients Foland-Ross et al, 2012;Vizueta et al, 2012).…”

Section: Discussionsupporting

confidence: 93%

“…In previous studies of conflict processing in bipolar disorder, euthymic patients demonstrated decreased activation in frontalparietal networks and basal ganglia structures when processing non-emotional conflict (Kronhaus et al, 2006;Pompei et al, 2011) and task-irrelevant emotional information (Malhi et al, 2005). In addition, abnormal connectivity between prefrontal and limbic/ paralimbic areas has been reported in euthymic patients during a Stroop task (Pompei et al, 2011b).…”

Section: Introductionmentioning

confidence: 90%

See 1 more Smart Citation

Modulation of brain response to emotional conflict as a function of current mood in bipolar disorder: Preliminary findings from a follow-up state-based fMRI study

Rey¹,

Desseilles²,

Favre³

et al. 2014

Psychiatry Research: Neuroimaging

View full text Add to dashboard Cite

a b s t r a c tWe used functional magnetic resonance imaging (fMRI) to examine affective control longitudinally in a group of patients with bipolar disorder (BD). Participants comprised 12 BD patients who underwent repeated fMRI scans in euthymic (n ¼ 11), depressed (n ¼9), or hypomanic (n ¼9) states, and were compared with 12 age-matched healthy controls. During fMRI, participants performed an emotional face-word interference task with either low or high attentional demands. Relative to healthy controls, patients showed decreased activation of the cognitive control network normally associated with conflict processing, more severely during hypomania than during depression, but regardless of level of task demand in both cases. During euthymia, a decreased response to conflict was observed only during the high load condition. Additionally, unlike healthy participants, patients exhibited deactivation in several key areas in response to emotion-conflict trials -including the rostral anterior cingulate cortex during euthymia, the hippocampus during depression, and the posterior cingulate cortex during hypomania. Our results indicate that the ability of BD patients to recruit control networks when processing affective conflict, and the abnormal suppression of activity in distinct components of the default mode network, may depend on their current clinical state and attentional demand.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 90%

Modulation of brain response to emotional conflict as a function of current mood in bipolar disorder: Preliminary findings from a follow-up state-based fMRI study

Rey¹,

Desseilles²,

Favre³

et al. 2014

Psychiatry Research: Neuroimaging

View full text Add to dashboard Cite

show abstract

“…147,149,150,155 Automatic emotion regulation paradigms. Two studies employing an emotional Stroop paradigm demonstrated decreased left OFC activity in euthymic BD adults, 157,158 which was associated with slower task performance. 158 Another study demonstrated decreased left MdPFC (BA10), and right VLPFC activity, although no performance deficit, in manic BD adults during risky decisionmaking-a gambling paradigm dependent upon automatic cognitive change as a strategy to maximize reward and minimize loss.…”

Section: Adult Bipolar Disordermentioning

confidence: 99%

A neural model of voluntary and automatic emotion regulation: implications for understanding the pathophysiology and neurodevelopment of bipolar disorder

2008

View full text Add to dashboard Cite

The ability to regulate emotions is an important part of adaptive functioning in society. Advances in cognitive and affective neuroscience and biological psychiatry have facilitated examination of neural systems that may be important for emotion regulation. In this critical review we first develop a neural model of emotion regulation that includes neural systems implicated in different voluntary and automatic emotion regulatory subprocesses. We then use this model as a theoretical framework to examine functional neural abnormalities in these neural systems that may predispose to the development of a major psychiatric disorder characterized by severe emotion dysregulation, bipolar disorder.

show abstract

“…The EST is a well-established paradigm to examine emotional processing [17][18][19] and attentional bias [20]. It has been frequently used in the field of emotional disorders [20] and also in chronic pain [21] which shares common features with tinnitus [22][23][24].…”

Section: Introductionmentioning

confidence: 99%

Neural correlates of tinnitus related distress: An fMRI-study

et al. 2013

View full text Add to dashboard Cite

Background: Chronic tinnitus affects 5 % of the population, 17 % suffer under the condition. This distress seems mainly to be dependent on negative cognitive-emotional evaluation of the tinnitus and selective attention to the tinnitus. A well-established paradigm to examine selective attention and emotional processing is the Emotional Stroop Task (EST). Recent models of tinnitus distress propose limbic, frontal and parietal regions to be more active in highly distressed tinnitus patients. Only a few studies have compared high and low distressed tinnitus patients. Thus, this study aimed to explore neural correlates of tinnitus-related distress.

show abstract

An emotional Stroop functional MRI study of euthymic bipolar disorder

Cited by 169 publications

References 84 publications

Modulation of brain response to emotional conflict as a function of current mood in bipolar disorder: Preliminary findings from a follow-up state-based fMRI study

Modulation of brain response to emotional conflict as a function of current mood in bipolar disorder: Preliminary findings from a follow-up state-based fMRI study

A neural model of voluntary and automatic emotion regulation: implications for understanding the pathophysiology and neurodevelopment of bipolar disorder

Neural correlates of tinnitus related distress: An fMRI-study

Contact Info

Product

Resources

About