An elegant and unprecedented approach to 2-methylbenzofurans

Iodocyclization of Diallyl-Dihydroxy Naphthalenes Using <i>N</i>-Iodosuccinimide vs Molecular Iodine in Aqueous Micelle

“…There are only few reports of the iodine-mediated heterocyclization in aqueous media [30,31] and also in organic media using additives [32,33] such as Envirocat EPZ-10 R or SnCl 4 [34][35][36]. The limitation of the traditional methods may be overcome by using surfactants as cosolvents.…”

Applications of metal and non-metal catalysts for the synthesis of oxygen containing five-membered polyheterocylces: a mini review

“…Tripathi et al [220] reported a 5-exo-trig cyclization of o-allyl phenols for the preparation of dihydro-benzofurans in water (Scheme 20). Products were obtained after the formation of iodoiranium intermediate followed by 5-exotrig cyclization.…”

Sulfoxide synthesis from sulfinate esters under Pummerer-like conditions

“…Iodine-mediated cyclization of the resulting phenol 20a and subsequent elimination with a base successfully furnished benzofuran 21. 17 Methallylation of sulfinate ester 10d followed by the aryne trifunctionalization led to the synthesis of highly functionalized phenol 20b (Fig. 5B).…”