An Electrochemical Comparison of Single‐Walled and Multi‐Walled Carbon Nanotubes Utilizing Paeonol as the Model Drug

Abstract

Herein, we report the development of a selective and highly sensitive electrochemical sensing of paeonol at carbon nanotubes modified glassy carbon electrode (GCE). Trace amount of paeonol was quantitated by employing square wave voltammetry technique for the first time based on the electrochemical oxidation of the analyte at the modified electrodes. The single walled carbon nanotubes (SWNTs) based sensor exhibited higher recognition ability of paeonol in comparison with the multi walled carbon nanotubes (MWNTs) based sensor. The linear dynamic range was found to be 100 nM – 25 μM for SWNTs modified GCE and 1–25 μM for MWNTs modified GCE. The sensitivity at SWNTs modified GCE was ∼ 3.5 times more than that at MWNTs modified GCE. The limit of detection was estimated to be 9.57 nM and 0.63 μM corresponding to SWNTs and MWNTs modified GCE respectively. The influence of experimental parameters affecting sensor response was optimized. The stability, reproducibility tests and interference effects were demonstrated to confirm the reliability of the proposed sensor. The applicability of the developed sensor was successfully assessed through convenient measurements of paeonol in biological samples and Cortex moutan which exhibits anticancer effect.

Selective fluoride ion sensing in aqueous medium using ultrathin film of functionalized single-walled carbon nanotubes

“…on It has been reported that the surface of the glassy carbon electrode was modified with multiwalled carbon nanotubes (MWCNTs) and a composite of MWCNTs with isothiocyanate and utilized them for Fion sensing using electrochemical platform [9]. Although the MWCNTs are cheaper, the sensing merits of SWCNTs are far better than that of MWCNTs [10][11][12]. Such enhanced performance is due to structural difference between them leading to improved physicochemical properties for sensing application.…”

Trace Level Recognition of Sulfasalazine Electrooxidation Exploiting the Synergism of Carbon Nanotubes and Iron Oxide Nanoparticles

“…Thus, in the current investigation a nano hybrid material of single walled carbon nanotubes (SWNTs) and Fe 3 O 4 nanoparticles along with nafion have been exploited for the first time for SSZ determination. SWNT is one of the most propitious candidates for the modification of sensors due to its potential features such as high electrical conductivity, remarkable electron transport capacity, significantly large surface area and excellent mechanical strength [26–30] . Fe 3 O 4 on the other hand, manifests strong adsorption ability, high abundance, low mass transfer resistance, biocompatibility, low toxicity and phenomenal magnetic and electrochemical properties [31–34] .…”

A Facile and Efficient Protocol for Preparing Residual-Free Single-Walled Carbon Nanotube Films for Stable Sensing Applications

“…The former consists of a single graphite sheet seamlessly wrapped into a cylindrical tube, while the latter comprises an array of such nanotubes that are concentrically nested like the rings of a tree trunk [8]. For sensing applications, SWCNTs promise a higher sensitivity compared with MWCNTs, which can be ascribed to their increased surface-to-volume ratio, and thus an increased number of unsaturated bonds that can act as reaction sites for the sensing specimen [16]. From an economic point of view, the increased sensitivity goes along with an increased product price, as the yield and the purity of SWCNT synthesis protocols is commonly lower than the ones for MWCNTs [17,18].…”