“…These catalysts have been used for one-pot multicomponent reactions (MCRs) (reagents: benzil, ammonium acetate and various aromatic aldehydes) for the synthesis of 2,4,5-trisubstituted imidazole molecules in a non- Nowadays, instead of using conventional catalysts such as Lewis or Brønsted acid and bases [48][49][50][51], the new generation of catalysts such as supported catalysts [52], polymerbased catalysts [53], metal-organic frameworks [54] and enzymes [55] have been used for various organic and inorganic transformations. In the literature, many synthetic methods have been reported for one-pot-multicomponent reactions of benzil, ammonium acetate and different aromatic aldehyde to synthesize 2,4,5-trisubstituted imidazoles under different reaction conditions [56][57][58][59][60][61][62][63][64][65][66][67][68][69][70][71][72]. In general, most procedures in the literature have their own advantages, but there are still some drawbacks in the literature procedures such as the use of non-reusable catalysts, long reaction times, hazardous solvents, harsh reaction conditions, high temperatures, the requirement of a large amount of catalyst and low yield of products.…”