An autonomous driven DNA walker-based electrochemical aptasensor for on-site detection of Ochratoxin A

Metal–organic frameworks on versatile substrates

“…2.1.1 Metal substrates. As expected, a diverse selection of different conducting metal substrates such as nickel (Ni), 51 zinc (Zn), 52 aluminum (Al), [53][54][55] gold (Au), [56][57][58][59][60][61] titanium (Ti), 62,63 copper (Cu), [64][65][66][67][68][69] Cu foams, [70][71][72][73][74] Ni foams, [75][76][77][78][79][80][81][82][83][84][85][86][87][88][89] and iridium (Ir) 90 have been proven to be excellent substrates to efficiently construct MOF crystals under specic conditions. To be mentioned, many self-sacricial materials can be used as both metal sources and substrates.…”

Tunable metal–organic frameworks assist in catalyzing DNAzymes with amplification platforms for biomedical applications

“…68,98,99 Relatively simple surface adsorption strategies possessed no strict requirements for the specific pore size or functional group type of MOFs. 100 In general, this can lead to a weaker interaction between the MOFs and Dzs, making it difficult to avoid the leaching problem. The size of the MOFs@Dzs determines the leaching problem based on the binding force between the MOFs and Dzs.…”

“…13(c)). 208 The intelligent system efficiently delivers the payload into cancer cells, and upon endocytosis, the MOFs disintegrate in response to the acidic endomembral/lysosomal environment and intracellular glutathione (GSH) release of therapeutic agents. 105 6.1.2.…”

Recent Progress of Covalent Organic Frameworks Applied in Electrochemical Sensors

“…In comparison to SPME and chromatography, COF-based electrochemical sensors have higher sensitivity, and in comparison to luminescent and colorimetric sensing, The working electrode plays an important role in the qualitative and quantitative detection performance of the sensor. Many advanced materials have been applied to prepare the working electrodes of electrochemical sensors, mainly including graphene, 64 carbon nanotubes (CNTs), 65 quantum dots (QDs), 66 metal nanoparticles (NPs), 67 metal oxides, 68 conductive polymers (CPs), 69 biomolecules, 70 enzyme, 71 black phosphorus, 72 Mxene, 73 polyoxometalates (POMs), 74 Perovskite, 75 MOFs, 76 COFs, 77 and so on. Compared with other materials, COFs possess excellent structural diversity, enabling them to be fine-tuned to meet specific sensing requirements.…”