An audit of <i>Chlamydia trachomatis</i> screening in colposcopy – Hartlepool experience

Tayal, S C; Robertson, A. A.; Doxford, Lynda

doi:10.1258/0956462054308350

Cited by 3 publications

(4 citation statements)

References 6 publications

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“…Chlamydia trachomatis is now considered an independent risk factor for the development of cervical cancer 34 . A recent study on colposcopy patients reporting a prevalence of 3.4%, suggested that routine screening for C. trachomatis be carried out in colposcopy clinics 35 . In our study, 20.4% of C. trachomatis infected samples were coinfected by HPV; however, no association was seen between C. trachomatis infection and abnormal cytology.…”

Section: Discussioncontrasting

confidence: 56%

“…34 A recent study on colposcopy patients reporting a prevalence of 3.4%, suggested that routine screening for C. trachomatis be carried out in colposcopy clinics. 35 In our study, 20.4% of C. trachomatis infected samples were coinfected by HPV; however, no association was seen between C. trachomatis infection and abnormal cytology. A recent study in Argentina found that prevalence of C. trachomatis was higher in HPV-infected cohorts.…”

Section: Discussionmentioning

confidence: 99%

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Chlamydia trachomatis detection in cervical PreservCyt specimens from an Irish urban female population

Keegan

Ryan²,

Malkin³

et al. 2009

Cytopathology

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Objective: The aim of this study was to determine the prevalence of cervical Chlamydia trachomatis infection by polymerase chain reaction (PCR) in urban women undergoing routine cervical cytological screening and to investigate the relationship with age, cytology, smoking status and concurrent human papillomavirus (HPV) infection. Methods: A total of 996 women (age range 16–69 years) attending general practitioners for routine liquid‐based cervical smear screening in the Dublin area were recruited in the study of prevalence of C. trachomatis. Informed consent was obtained and liquid‐based cytology (LBC) specimens were sent for cytological screening. DNA was extracted from residual LBC and tested for C. trachomatis by PCR using the highly sensitive C. trachomatis plasmid (CTP) primers and for HPV infection using the MY09/11 primers directed to the HPV L1 gene in a multiplex format. Results: The overall prevalence of C. trachomatis was 5.4%. Prevalence was highest in the <25 years age group (10%). Coinfection with HPV and C. trachomatis occurred in 1% of the screening population. A higher rate of smoking was observed in women positive for C. trachomatis, HPV infections or those with abnormal cervical cytology. Chlamydia trachomatis infection was not associated with abnormal cytology. Conclusions: Women (5.4%) presenting for routine cervical screening are infected with C. trachomatis. Opportunistic screening for C. trachomatis from PreservCyt sample taken at the time of cervical cytological screening may be a possible strategy to screen for C. trachomatis in the Irish female population.

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Section: Discussioncontrasting

confidence: 56%

Section: Discussionmentioning

confidence: 99%

Chlamydia trachomatis detection in cervical PreservCyt specimens from an Irish urban female population

Keegan

Ryan²,

Malkin³

et al. 2009

Cytopathology

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“…Some colposcopists may repeat a Pap test during the examination; however, both retrospective and prospective studies have shown limited clinical utility in repeating either liquid‐based or conventional cytology at the time of colposcopy 18–20 . Screening for gonorrhea and chlamydia may be considered in high‐risk populations 21–23 …”

Section: Visualization With Colposcopymentioning

confidence: 99%

“… Sources: American College of Obstetricians and Gynecologists, 2 Tayal et al, 22 the American Academy of Family Physicians, 39 Templeton and Williams, 40 and Duerr et al 41 …”

Section: Introductionmentioning

confidence: 99%

The Colposcopic Examination

Frank

2008

J Midwife Womens Health

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Colposcopy is used to evaluate women with genital tract abnormalities and abnormal cervical cytology. It is an office-based procedure during which the cervix is examined under illumination and magnification before and after application of dilute acetic acid. Colposcopy may include a biopsy of lesions with characteristics of malignancy and premalignancy, such as acetowhite changes, abnormal vascular patterns, and failure to uptake iodine stain. Endocervical sampling may accompany colposcopy, particularly in the evaluation of nonpregnant women with cytology results of atypical glandular cells and adenocarcinoma in situ. Satisfactory colposcopy requires visualization of the entire squamocolumnar junction and margins of any visible lesions. While most midwives do not perform colposcopy, they will provide the pre- and postprocedure education, counseling, and evaluation of patients undergoing the procedure. This paper reviews essential information and gives special consideration to colposcopic examination in adolescent women, pregnant women, and postmenopausal women.

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