An attempt to inactivate mimosine of Leucaena leucocephala by mineral supplementation for feeding to ruminants

Samanta, A.K.; Chopra, R.C.; Atreja, P.P.; Chhabra, Aruna

doi:10.1016/0377-8401(94)90016-7

Cited by 6 publications

(2 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In ruminants, mimosine is degraded in the rumen (Hegarty et al 1964; Ram et al 1994; Samanta et al 1994; Feng & Atreja 1998; Gupta & Atreja 1998), 3,4-DHP (Hegarty et al 1979; Jones & Hegarty 1984; Gupta & Atreja 1998) and 2,3-DHP (Jones & Hegarty 1984; D'Mello, 1992) to various metabolites. Mimosine and its metabolites may be absorbed through the rumen wall, pass to the lower gut to be absorbed there, or excreted in the faeces.…”

Section: Discussionmentioning

confidence: 99%

“…An increase was also observed in terms of SNF, protein, total solids (Rai et al 1994) and fats which may be due to higher digestible protein and TDN values of leucaena (Singh & Mudgal 1967; Upadhayaya et al 1974; Sobale et al 1978; Deshmukh et al 1983; Rodriguez & Borges 1989). The increase in fat might be due to increased acetate proportion in the leucaena-based diet (Gupta et al 1986; Pathak et al 1988; Samanta et al 1994; Senani & Joshi 1995; Gupta & Atreja 1998) by enhancing supply of fat precursors in the mammary gland (McDonald et al 1995). However, all these beneficial effects may be nullified if the recorded levels of mimosine, 3,4-DHP and 2,3-DHP have an untoward influence on the offspring of the animals or human health.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Influence of short-term Leucaena leucocephala feeding on milk yield and its composition, thyroid hormones, enzyme activity, and secretion of mimosine and its metabolites in milk of cattle

et al. 2007

View full text Add to dashboard Cite

SU MMARYFour Karan/Friesian crossbred (HolsteinrTharparkar) dairy cows in late lactation (>200 days) were fed a basic diet of green maize and concentrates with an increasing proportion of Leucaena leucocephala (leucaena) leaf meal (LLM). The proportion was gradually increased from 0 . 25 of the dry matter intake (DMI) in the first week to 0 . 50 in the second, 0 . 75 in the third and ad libitum in the fourth week. Mimosine, 3,4-dihydroxy pyridine (3,4-DHP) and 2,3-dihydroxy pyridone (2,3-DHP) levels were determined in milk, serum, urine and faecal samples. On average DMI of leucaena was 0 . 023-0 . 025, 0 . 025-0 . 027, 0 . 027-0 . 028 and 0 . 022-0 . 025 of live weight (LW) during the first, second, third and fourth week, respectively. Mimosine, 3,4-DHP and 2,3-DHP appeared in the blood serum during leucaena feeding and continued appearing up to sixth week of experimental feeding even after the withdrawal of leucaena from the 34th day onwards. Similarly, excretion of mimosine, 3,4-DHP and 2,3-DHP were observed even after withdrawal of leucaena from the diet. The feeding of LLM resulted in a reduced level of T 3 (Triiodothyronine) and T 4 (Thyroxine) within a week of LLM feeding. The level of T 3 and T 4 improved to normal after withdrawal of LLM from the diet. The serum aspartate transferase (AST) and serum alanine transferase (ALT) activities were within the normal range. Leucaena feeding improved milk yield and composition only up to 3 weeks of feeding. The concentration of mimosine, 3,4-DHP and 2,3-DHP in milk was 0 . 33, 0 . 05 and 0 . 02 that of blood, respectively. The secretion of mimosine, 3,4-DHP and 2,3-DHP in the milk might be a concern for health of the offspring of leucaena-fed animals as well as human beings consuming such milk.

show abstract