The incidence of inflammatory skin diseases is increasing, so the search for relevant therapeutics is of
major concern. Plants are rich in phytochemicals which can alleviate many symptoms. In this review, we concentrate
on compounds found in the seeds of widely cultivated plants, regularly used for oil production. The oils from
these plants are often used to alleviate the symptoms of inflammatory diseases through synergetic action of unsaturated
fatty acids and other phytochemicals most commonly derived from the terpenoid pathway. The knowledge
of the chemical composition of oil seeds and the understanding of the mechanisms of action of single components
should allow for a more tailored approach for the treatment for many diseases. In many cases, these seeds
could serve as an efficient material for the isolation of pure phytochemicals. Here we present the content of phytochemicals,
assumed to be responsible for healing properties of plant oils in a widely cultivated oil seed plants
and review the proposed mechanism of action for fatty acids, selected mono-, sesqui-, di- and triterpenes, carotenoids,
tocopherol and polyphenols.