An Assessment of the Number of Cariogenic Bacteria in the Saliva of Children with Chemotherapy-Induced Neutropenia

The impact of chemotherapeutic treatment on the oral microbiota of patients with cancer: a systematic review

“…In total, 2966 studies were screened; of these, 2932 were excluded after review of the tittles or abstracts. The full texts of the remaining 34 publications [7][8][9][10]13, were reviewed; of these, 17 studies 7,8,10,13,18,23,27,28,31,[33][34][35][36]39,42,44,45 were included, and 17 9,[19][20][21][22][24][25][26]29,30,32,37,38,40,41,43,46 were excluded for different reasons (10 studies 9,19,21,22,29,30,38,40,41,46 for not fulfilling the proposed inclusion criteria, and 7 because they were published in other languages: Hungarian, Polish, German, Italian…”

“…Of the 17 studies 7,8,10,13,18,23,27,28,31,[33][34][35][36]39,42,44,45 included in this systematic review, 9 studies were specifically on hematologic malignancies, 7,8,13,18,27,34,35,42,45 3 studies were specifically on solid tumors, 10,23,44 2 studies did not mention the type of malignancy, 28,39 and 3 studies included solid tumors and hematologic malignancies. 31,33,36 A total of 359 patients, with different types of malignancies, were studied: 251 patients with hematologic malignancies 7,8,13,18,27,31,[33][34][35][36]42,45 (acute nonlymphocytic leukemia, acute lymphocytic leukemia, acute myeloid leukemia, lymphocytic leukemia, chronic myelogenous leukemia, and lymphoma) and 108 patients with different diagnoses of solid tumors 10,23,31,…”

Efeitos do tratamento periodontal não-cirúrgico sobre o perfil de citocinas inflamatórias em pacientes com periodontite crônica e câncer de mama submetidos à quimioterapia

“…From 17 studies included, 11 case-control 8,20,28,29,34,35,40,43,45,46,48 studies and 6 cross sectional studies 12,15,18,32,36,37 .…”

“…Of the studies included twelve studies specified the chemotherapeutic drugs used and the other five 12,20,34,43,46 did not specify. The chemotherapeutic used were: Cytosine arabinoside 36 , aclarubicin 52 , cytarabine 52 , daunorubicin 53 , vincristine, asparaginase 53 , cyclophosphamide 24, 28, 54 , 29 FRALLE 93 protocol, LAME 91 protocol 8 , epirubicin or methotrexate 24,28,29 , 5-fluorouracil 24,29,40,55 , Docetaxel and oxaliplatin 55 , adriamycin 15,29,40 , cytoxan 15 , vinblastine 40 , methotrexate 40 , UMCC protocols 37 .…”

“…Of the studies included in this systematic review, five studies were conducted in pediatric patients and twelve studies in adult patients. Of these, all pediatric patients 8,28,34,35,43 were included in an oral hygiene program, which consisted of the instruction of brushing and use of chlorhexidine 0.2% from 1 to 4 times a day. One study 46 in adult patients used chlorhexidine twice daily.…”