An assessment of risk factors for the complexity of coronary artery disease using the SYNTAX score

Tanaka, Tetsuya; Seto, Shinji; Yamamoto, Kazuki; Kondo, Masanori; Otomo, Toshiyuki

doi:10.1007/s12928-012-0112-5

Cited by 27 publications

(29 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A more complex disease pattern, reflected by a higher SS, is therefore expected in patients with a higher risk profile. The evidence associating SS with a higher risk profile, is however still scarce [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Classical determinants of coronary artery disease as predictors of complexity of coronary lesions, assessed with the SYNTAX score

et al. 2017

View full text Add to dashboard Cite

Background We need new biomarkers that can predict cardiovascular disease to improve both diagnosis and therapeutic strategies. The CIRCULATING CELLS study was designed to study the role of several cellular mediators of atherosclerosis as biomarkers of coronary artery disease (CAD). An objective and reproducible method for the quantification of CAD extension is required to establish relationships with these potential biomarkers. We sought to analyse the correlation of the SYNTAX score with known CAD risk factors to test it as a valid marker of CAD extension. Methods and results A subgroup of 279 patients (67.4% males) were included in our analysis. Main exclusion criteria were a history of previous percutaneous coronary intervention or surgical revascularisation that prevent an accurate assessment of the SS. Diabetes mellitus, smoking, renal insufficiency, body mass index and a history of CAD and myocardial infarction were all positively and strongly associated with a higher SYNTAX score after adjustment for the non-modifiable biological factors (age and sex). In the multivariate model, age and male sex, along with smok- Conclusion In a selected cohort of revascularisation-naive patients with CAD undergoing coronary angiography, nonmodifiable cardiovascular risk factors such as advanced age, male sex, as well as smoking and renal failure were independently associated with CAD complexity assessed by the SYNTAX score. The SYNTAX score may be a valid marker of CAD extension to establish relationships with potential novel biomarkers of coronary atherosclerosis.

show abstract

Section: Introductionmentioning

confidence: 99%

Classical determinants of coronary artery disease as predictors of complexity of coronary lesions, assessed with the SYNTAX score

et al. 2017

View full text Add to dashboard Cite

show abstract

“…A higher patient's risk status is expected to be accompanied by a more severe and advanced form of the disease and a higher SX score. The evidence regarding such statement is still not that sufficient [14].…”

Section: Discussionmentioning

confidence: 99%

Correlation between SYNTAX Score and Pattern of Risk Factors in Patients Referred for Coronary Angiography in Cardiology Department, Menoufia University

Kersh¹,

Reda²,

Hadad³

et al. 2018

WJCD

View full text Add to dashboard Cite

Objectives: The role of SYNTAX (SX) score in assessing the complexity of coronary artery disease (CAD) is well established. In this study we investigate the relationship between conventional risk factors of CAD with its complexity using SX score. Methods: The study consisted of 52 patients with CAD who were admitted to Cardiology Department-Menoufia University Hospitals for elective coronary angiography. The overall SX score was calculated prospectively using the SX score algorithm. Then comparison was done between populations with and without each risk factor. Results: There was a statistically significant correlation between age, hypertension, diabetes mellitus, dyslipidemia and smoking with SX score results (p < 0.05) and an insignificant correlation regarding body mass index and gender (p > 0.05). In a multivariate regression analysis, including conventional risk factors of CAD as independent covariates, it revealed that aging, having diabetes mellitus and smoking were identified as significant independent risk factors for CAD complexity. Conclusion: Advanced age, having diabetes mellitus and cigarette smoking are considered to be independent risk factors for the complexity of CAD. Therefore, when these factors present, we expect that the SX score of the patient to be high indicating a complex CAD.

show abstract

“…Similar to other studies' ndings (8,10), the patients in this study undergoing AT were older, have higher Charlson comorbidity index, and poor ASA PS than those who were not undergoing AT (Table 2). Advanced age is a well-known risk factor of cardiovascular disease, such as stroke (25) and coronary artery disease (26).…”

Section: Discussionmentioning

confidence: 99%

Emergency Gastrointestinal Surgery in Patients Undergoing Antithrombotic Therapy in a Single General Hospital: A Propensity Score-Matched Analysis

Abe

Ami

Katsuno

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: This study aimed to review and evaluate the surgical outcomes, particularly intraoperative severe blood loss and postoperative blood complications, of emergency gastrointestinal surgery in patients undergoing antithrombotic therapy (AT). Emergency surgeries for patients with antithrombotic medication have been increasing in the aging population. However, the effect of AT on intraoperative blood loss and perioperative complications remains unclear.Methods: We retrospectively reviewed 732 patients who underwent emergency gastrointestinal surgery between April 2014 and March 2019. Patients were classified into AT group and Non-AT group, and propensity score-matched analysis was performed to compare the short surgical outcomes between the groups. Additionally, risk factors in severe estimated blood loss (EBL) were assessed. The optimal value of EBL was determined using the receiver operating characteristic curve.Results: Altogether, 64 patients received AT; 50 patients and 12, and 2 were given antiplatelet and anticoagulant, and both drugs, respectively. After propensity score matching, EBL (101 vs. 99 ml; p = 0.466) and postoperative complications (14 vs. 16 patients; p = 0.676) were similar between the groups (63 patients matched paired). Intraoperative severe bleeding (EBL ≥ 113 ml) occurred in 146 patients. Multivariate analysis using the full cohort revealed that anticoagulant drug use was an independent risk factor for severe bleeding (odds ratio, 6.50; 95% CI 1.4 - 36; p = 0.015). Conclusions: This study demonstrated antithrombotic drugs do not adversely affect the perioperative outcomes of emergency gastrointestinal surgery, although patients taking anticoagulant drugs or multiple antithrombotic drugs should undergo careful surgical performances and postoperative management.

show abstract

An assessment of risk factors for the complexity of coronary artery disease using the SYNTAX score

Cited by 27 publications

References 37 publications

Classical determinants of coronary artery disease as predictors of complexity of coronary lesions, assessed with the SYNTAX score

Classical determinants of coronary artery disease as predictors of complexity of coronary lesions, assessed with the SYNTAX score

Correlation between SYNTAX Score and Pattern of Risk Factors in Patients Referred for Coronary Angiography in Cardiology Department, Menoufia University

Emergency Gastrointestinal Surgery in Patients Undergoing Antithrombotic Therapy in a Single General Hospital: A Propensity Score-Matched Analysis

Contact Info

Product

Resources

About