Correlation between SYNTAX Score and Pattern of Risk Factors in Patients Referred for Coronary Angiography in Cardiology Department, Menoufia University

Kersh, Ahmed Mokhtar El; Reda, Ahmed; Hadad, Mohamed Gamal El; El-Sharnouby, Khaled Hussein

doi:10.4236/wjcd.2018.88042

Cited by 9 publications

(19 citation statements)

References 23 publications

(21 reference statements)

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“…Another positive correlation was present between SYNTAX score and smoking (p = 0.001); this was found in several studies, among them El Kersh et al [22], where a statistically significant correlation between age, hypertension, diabetes mellitus, dyslipidemia, and smoking with SYNTAX score was noticed (p < 0.05).…”

Section: Discussionmentioning

confidence: 65%

Correlation between global longitudinal strain and SYNTAX score in coronary artery disease evaluation

2020

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Background Speckle tracking echocardiography may allow the evaluation of myocardial systolic and diastolic dynamics across different physiologic and pathologic conditions beyond traditional echocardiographic techniques. The use of STE longitudinal strain in identification and risk stratification of CAD has good reproducibility and accuracy. The study aims to detect the relationship between SYNTAX score and global longitudinal peak systolic strain (GLPSS) in patients undergoing coronary angiography, with no history of myocardial infarction. Results The study included 70 symptomatic patients suspected to have chronic coronary syndrome aging 20–80 years (excluding those with significant structural heart disease). All patients underwent clinical evaluation, surface ECG, laboratory assessment, transthoracic echocardiographic (TTE), color TDI tracings, two-dimensional speckle tracking, and conventional coronary angiography with SYNTAX score calculation. Patients were divided into 3 groups based on the results of the coronary angiogram: normal CAD on angiogram (n = 10, control group), low SS (n = 25, SS < 22), and high SS (n = 35, SS ≥ 22). The mean age was 55 ± 9.6 years; 54% were males; two third of patients were hypertensive; 52% were diabetic; high percentage of high syntax score were noticed among males, diabetic patients, and smokers; and also low mean of GLS was noticed among diabetic patients and smokers. There was a statistically significant positive correlation between syntax score and each of LVEDD and LVESD and, on the other hand, statistically significant negative correlation between syntax score and each of E/A, GLS, AP2LS, AP3LS, and AP4LS was noticed. Peak GLS cutoff value of 17.8 and 16.5 showed 84% and 93% sensitivity and 70% and 91% specificity to detect high and low syntax score, respectively. Conclusion 2D longitudinal strain analysis has incremental diagnostic value over visual assessment during echocardiography in predicting significant coronary artery disease; GLS may offer a potential sensitive tool to detect significant CAD.

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Section: Discussionmentioning

confidence: 65%

Correlation between global longitudinal strain and SYNTAX score in coronary artery disease evaluation

2020

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“…In a recent study by: El Kersh, A., Reda, A., El Hadad, M. et al [13] they investigated the relationship between conventional risk factors of CAD with its complexity using SYNTAX score. In 52 ischemic heart disease patients who admitted to elective coronary angiography.…”

Section: Discussionmentioning

confidence: 99%

Acute Coronary Syndrome in Egyptian Women during their Reproductive Age Period

Essa

Ashmawy

Salama

et al. 2022

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Background: Young women have low risk of acute coronary syndrome (ACS) during their reproductive period, mainly due to the physiologically protective effect of estrogen hormone on the coronary endothelium. The purpose of this study was to assess the risk factors of ACS in the Egyptian women patients during their reproductive age period, who admitted to Tanta University Cardiovascular department hospital. Results: Obesity, hypertension, diabetes mellitus, chronic kidney disease, systemic lupus erythematosus, myocardial bridge, cushion syndrome and radiotherapy for breast cancer were significantly independently ACS risk factors that correlated to the SYNTAX score. There is significance of coefficient of the independent variable in the risk factors (Group A, group B, group C separately and groups A, B, C together) on the severity and level of SYNTAX score in ACS. The regression analysis was significant in groups A and B of ACS risk factors separately. While the regression analysis was significant and there was a clear relationship between ACS risk factors- groups A, B, C. together and SYNTAX score. Conclusions: There was a positive relationship between the increase total number of ACS risk factors subgroups (Traditional, Nontraditional and Gynecological) and the severity of coronary artery stenosis that assessed by SYNTAX scorer.

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“…To the best of our knowledge, this is the first study to demonstrate that CHA 2 DS 2 -VASc-HSF offers better predictive accuracy than GRS 1.0 in determining the CAD severity. We believe that this finding could be attributable to the fact that the CHA 2 DS 2 -VASc-HSF score is a model that includes a combination of several factors related to the CAD severity, such as HT, DM, hyperlipidemia, positive family history, HF, stroke, and history of CAD and CAD-equivalent vascular diseases, compared with GRS 1.0 (31)(32)(33)(34)(35) . Indeed, DM, hyperlipidemia, HF, HT, and vascular disease were found to be significantly related to intermediate-high SSI.…”

Section: Discussionmentioning

confidence: 99%

Predictive Accuracy of the CHA2 DS2 -VASc-HSF Score in Determining One-Year Cardiovascular Outcomes in Patients with Non-ST-Elevation Acute Coronary Syndrome: A Retrospective Study

Kalyoncuoğlu¹,

Durmuş²,

Belen³

et al. 2020

Kosuyolu Heart Journal

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Introduction: To investigate the predictive accuracy of the CHA 2 DS 2 -VASc-HSF score in predicting the one-year mortality and major adverse cardiac and cerebrovascular events (MACCEs) in patients with non-STelevation acute coronary syndrome (NSTE-ACS). Patients and Methods:In this retrospective study, the study cohort was divided in to two groups based on the median CHA 2 DS 2 -VASc-HSF score: low-risk group (≤ 4 points) and high-risk group (> 4 points). Results:We enrolled 394 patients with NSTE-ACS (mean age: 58.7 ± 11.8 years). The CHA 2 DS 2 -VASc-HSF score independently predicted the coronary artery disease (CAD) severity (p< 0.01), one-year mortality (p< 0.01), and MACCEs (p< 0.01). The Global Registry for Acute Coronary Events (GRACE) risk score (GRS 1.0) independently predicted the CAD severity (p< 0.01), whereas the revised GRACE 2.0 risk score (GRS 2.0) independently predicted the one-year mortality (p< 0.01) and MACCEs (p< 0.01). The diagnostic performance of CHA 2 DS 2 -VASc-HSF was similar to GRS 2.0 in predicting the one-year mortality and MACCEs [area under the curve (AUC), 0.75 and 0.69 vs. 0.78 and 0.67; p= 0.41, p= 0.38, respectively) and better than GRS 1.0 for the CAD severity (AUC, 0.85 vs. 0.79; p= 0.03). The Kaplan-Meier curves displayed significantly higher one-year mortality and MACCEs in the high-risk group (p< 0.01) compared with the low-risk group (p< 0.01). Conclusion:The predictive accuracy of CHA 2 DS 2 -VASc-HSF is comparable to that of GRS 2.0 in determining the long-term cardiovascular outcomes; thus, it could be considered as a predictive model for patients with NSTE-ACS.

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Correlation between SYNTAX Score and Pattern of Risk Factors in Patients Referred for Coronary Angiography in Cardiology Department, Menoufia University

Cited by 9 publications

References 23 publications

Correlation between global longitudinal strain and SYNTAX score in coronary artery disease evaluation

Correlation between global longitudinal strain and SYNTAX score in coronary artery disease evaluation

Acute Coronary Syndrome in Egyptian Women during their Reproductive Age Period

Predictive Accuracy of the CHA2 DS2 -VASc-HSF Score in Determining One-Year Cardiovascular Outcomes in Patients with Non-ST-Elevation Acute Coronary Syndrome: A Retrospective Study

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