An approach to investigating the importance of high potency polycyclic aromatic hydrocarbons (PAHs) in the induction of lung cancer by air pollution

Okona-Mensah, K.B.; Battershill, Jon M.; Boobis, Alan R.; Fielder, R.J.

doi:10.1016/j.fct.2005.03.001

“…The highest concentration appeared in a plaza (site 19) in the southern part for both PM 2.5 and PM 10 while the lowest dose detected in a village (site 5) for PM 2.5 and a residential area (site 14) for PM 10 . Average concentration of individual OCPs was listed in Table 2.…”

Section: Ocps Concentrationmentioning

confidence: 99%

“…The industrial emission was the possible reason for the high levels there. A village site (site 5) and another industrial site (site 11) had the lowest concentrations for PM 2.5 and PM 10 , respectively.…”

Section: Chlordanesmentioning

confidence: 99%

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Organochlorine pesticides in particulate matter of Beijing, China

Wang

¹

,

Li

²

,

Cheng

³

et al. 2008

Journal of Hazardous Materials

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Eighteen organochlorine pesticides (OCPs) in air particulate matter (PM) samples collected from 20 sites in Beijing, China in 2005 and 2006 were analyzed to determine the composition, spatial distribution and sources. Total OCPs of PM 2.5 and PM 10 ranged from 32.59 pg m −3 to 9232.31 pg m −3 and 80.96 pg m −3 to 9434.97 pg m −3 , respectively, categorized as heavier pollution compared to other cities of China. Among six kinds of functional zones involved, commercial areas and industrial centers were heavily polluted. Distinct concentrations variations were detected in PM with different particle diameters. Pollution distribution was spatially heterogeneous inside the city. The most heavily polluted sites located in the southeast part of the city, where laid many chemical factories. Compositional analysis and principal component analysis (PCA) suggested that past usage of OCPs was the main source, though there were new inputs in some sites.

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“…However, the suitability of benzo(a)pyrene as an indicator of carcinogenic PAHs has been questioned by new findings on the presence of more potent PAHs such as dibenzo(a,l)pyrene [8]. It has been estimated to have a carcinogenic potency that is approximately 100 times that of benzo(a)pyrene [9]. Until now, however, ticles were collected on PTFE membrane filters with 2 lm porosity [20].…”

Section: Introductionmentioning

confidence: 99%

Analysis of polycyclic aromatic hydrocarbons in atmospheric particulate samples by microwave‐assisted extraction and liquid chromatography

Castro

¹

,

Slezáková

²

,

Oliva-Teles

³

et al. 2009

J of Separation Science

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A methodology based on microwave-assisted extraction (MAE) and LC with fluorescence detection (FLD) was investigated for the efficient determination of 15 polycyclic aromatic hydrocarbons (PAHs) regarded as priority pollutants by the US Environmental Protection Agency and dibenzo(a,l)pyrene in atmospheric particulate samples. PAHs were successfully extracted from real outdoor particulate matter (PM) samples with recoveries ranging from 81.4 l 8.8 to 112.0 l 1.1%, for all the compounds except for naphthalene (62.3 l 18.0%) and anthracene (67.3 l 5.7%), under the optimum MAE conditions (30.0 mL of ACN for 20 min at 1108C). No clean-up steps were necessary prior to LC analysis. LOQs ranging from 0.0054 ng/m 3 for benzo(a)anthracene to 0.089 ng/m 3 for naphthalene were reached. The validated MAE methodology was applied to the determination of PAHs from a set of real world PM samples collected in Oporto (north of Portugal). The sum of particulate-bound PAHs in outdoor PM ranged from 2.5 and 28 ng/m 3 .

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“…[7][8][9]. Atmospheric particles plays an important role in OCPs transportation [6], and they are believed to have relevance with many lung dieses [10]. Thus, measurements of OCPs in particulate matters of high population load are necessary.…”

Section: Introductionmentioning

confidence: 99%

Organochlorine Pesticides in the Soil in Linfen, China

Cheng

¹

,

Fu

²

,

Liu

³

et al. 2008

Bull Environ Contam Toxicol

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Eighteen organochlorine pesticides (OCPs) in air particulate matter (PM) samples collected from 20 sites in Beijing, China in 2005 and 2006 were analyzed to determine the composition, spatial distribution and sources. Total OCPs of PM 2.5 and PM 10 ranged from 32.59 pg m −3 to 9232.31 pg m −3 and 80.96 pg m −3 to 9434.97 pg m −3 , respectively, categorized as heavier pollution compared to other cities of China. Among six kinds of functional zones involved, commercial areas and industrial centers were heavily polluted. Distinct concentrations variations were detected in PM with different particle diameters. Pollution distribution was spatially heterogeneous inside the city. The most heavily polluted sites located in the southeast part of the city, where laid many chemical factories. Compositional analysis and principal component analysis (PCA) suggested that past usage of OCPs was the main source, though there were new inputs in some sites.

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An approach to investigating the importance of high potency polycyclic aromatic hydrocarbons (PAHs) in the induction of lung cancer by air pollution

Cited by 160 publications

References 81 publications

Organochlorine pesticides in particulate matter of Beijing, China

Organochlorine pesticides in particulate matter of Beijing, China

Analysis of polycyclic aromatic hydrocarbons in atmospheric particulate samples by microwave‐assisted extraction and liquid chromatography

Organochlorine Pesticides in the Soil in Linfen, China

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