1947
DOI: 10.1007/bf03001282
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An appraisal of the value of diagnostic biliary drainage

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1953
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“…For many years clinicians have examined bile collected from patients by a tube passed perorally into the duodenum (the Meltzer-Lyon test) (13,(19)(20)(21)(22)(23)(24)(25)(26)(27). When gallbladder bile contains cholesterol crystals or calcium bilirubinate granules in moderate to large amounts, there is a strong correlation with the presence of gallstones in the gallbladder or some other abnormality, such as cholesterolosis (19)(20)(21). Even though supersaturation of bile with cholesterol is very common in humans during fasting (281, cholesterol crystals usually do not develop except in those with gallstone disease 129).…”
Section: Discussionmentioning
confidence: 99%
“…For many years clinicians have examined bile collected from patients by a tube passed perorally into the duodenum (the Meltzer-Lyon test) (13,(19)(20)(21)(22)(23)(24)(25)(26)(27). When gallbladder bile contains cholesterol crystals or calcium bilirubinate granules in moderate to large amounts, there is a strong correlation with the presence of gallstones in the gallbladder or some other abnormality, such as cholesterolosis (19)(20)(21). Even though supersaturation of bile with cholesterol is very common in humans during fasting (281, cholesterol crystals usually do not develop except in those with gallstone disease 129).…”
Section: Discussionmentioning
confidence: 99%