An Anticalculus Dentifrice with Sodium Hexametaphosphate and Stannous Fluoride: A Six-month Study of Efficacy

Emilson

et al. 2019

Heliyon

ObjectivesThe aim of the present systematic review was to examine the scientific evidence for the efficacy of stabilized stannous fluoride (SnF2) dentifrice in relation to dental calculus, dental plaque, gingivitis, halitosis and staining.Data and sourcesMedline OVID, Embase.com, and the Cochrane Library were searched from database inception until June 2017. Six researchers independently selected studies, extracted data, and assessed methodological quality. A meta-analysis of the 6-month gingivitis studies was done. Risk of bias was estimated using a checklist from the Swedish Agency for Health Technology Assessment (SBU, 2018).Study selectionTwo studies on dental calculus, 21 on dental plaque and gingivitis, 4 on halitosis, and 5 on stain met the inclusion criteria. Risk of bias was high for the studies on dental calculus, halitosis, and stain, and varied for the dental plaque and gingivitis studies. Significant reductions in dental calculus and in halitosis were reported for the SnF2 dentifrice; no differences in stain reduction were noted. A meta-analysis on gingivitis found better results for the SnF2 dentifrice compared to other dentifrices, though the results of the individual trials in the meta-analyses showed a substantial heterogeneity.ConclusionsThe present review found that stabilized SnF2 toothpaste had a positive effect on the reduction of dental calculus build-up, dental plaque, gingivitis, stain and halitosis. A tendency towards a more pronounced effect than using toothpastes not containing SnF2 was found. However, a new generation of well conducted randomized trials are needed to further support these findings.Clinical relevanceAdding a SnF2 toothpaste to the daily oral care routine is an easy strategy that may have multiple oral health benefits.

Section: Resultsmentioning

confidence: 99%

“…In the Winston et al. [37] study, home-based and unsupervised use of a SnF 2 dentifrice during normal hygiene procedures effectively inhibited calculus regardless of the baseline levels of calculus. The significant anti-calculus efficacy that was observed is further evidence of the capacity of SHMP to interfere with calculus formation.…”

Section: Discussionmentioning

confidence: 99%

Effects of stabilized stannous fluoride dentifrice on dental calculus, dental plaque, gingivitis, halitosis and stain: A systematic review

Emilson

et al. 2019

Heliyon

“…Adding an SnF 2 toothpaste to the daily oral care regimen has been shown to have multiple oral health benefits including reduction of dental calculus buildup, dental plaque, gingivitis, staining, and halitosis. A recent systematic review found evidence that significant reduction in calculus formation was produced by a toothpaste containing SnF 2 and a calcium phosphate mineralization inhibitor (SHMP) [ 112 ]. The SnF 2 + SHMP toothpaste also showed to play an important role in stain reduction [ 113 , 114 ].…”

Section: Fluoridesmentioning

confidence: 99%

Recent Development of Active Ingredients in Mouthwashes and Toothpastes for Periodontal Diseases

et al. 2021

Periodontal diseases like gingivitis and periodontitis are primarily caused by dental plaque. Several antiplaque and anti-microbial agents have been successfully incorporated into toothpastes and mouthwashes to control plaque biofilms and to prevent and treat gingivitis and periodontitis. The aim of this article was to review recent developments in the antiplaque, anti-gingivitis, and anti-periodontitis properties of some common compounds in toothpastes and mouthwashes by evaluating basic and clinical studies, especially the ones published in the past five years. The common active ingredients in toothpastes and mouthwashes included in this review are chlorhexidine, cetylpyridinium chloride, sodium fluoride, stannous fluoride, stannous chloride, zinc oxide, zinc chloride, and two herbs—licorice and curcumin. We believe this comprehensive review will provide useful up-to-date information for dental care professionals and the general public regarding the major oral care products on the market that are in daily use.

“…It must be removed with hand, sonic or ultrasonic instruments, procedures which are labor and time consuming and costly. Consequently, there has been considerable interest in formulas, mostly incorporated in dentifrices, containing zinc citrate, chlorohexidine, bisphosphonates, pyrophosphates, triclosan, polymers and copolymers attempting either to inhibit or retard the formation and accumulation of calculus [6][7][8][9][10][11]. These agents appear to reduce the formation of supragingival calculus by 30-50%, the variance probably due to differences in study design [12].…”

Section: Introductionmentioning

confidence: 99%

Efficacy of a Rinse Containing Tetrapotassium Pyrophosphate and Sodium Tripolyphosphate on Calculus Formation in a Group of Adults

Hoover¹,

Yarie²,

Hooper³

et al. 2020

DOBCR

Objectives: To evaluate a mouth rinse containing tetrapotassium pyrophosphate and sodium tripolyphosphate on supragingival calculus formation in a group consisting initially of forty adults seeking periodontal treatment at a Canadian dental school. Methods: The extent of supragingival calculus in relation to the lingual surfaces of the lower anterior teeth was measured using the Volpe-Manhold Calculus Index (VMI). In addition, The Plaque Index (PI) was used to evaluate plaque scores while the presence or absence of gingival bleeding index (GBI) was used to determine gingival health. At the completion of the hygiene appointment (baseline), the PI, GBI and VMI was assumed to be zero and the subjects were randomly assigned to test (rinsed twice a day with the anticalculus mouthwash) or control groups (only used regular dentifrice) and appropriate instructions provided. After a 60-day trial period, the test and control subjects were recalled, and the clinical measurements were conducted using the indices indicated above. Results: There were no statistically significant differences in the overall reduction in the mean VMI scores between the test and control groups. Conclusion: Within the limitations of the study, rinsing with tetrapotassium pyrophosphate and sodium tripolyphosphate for sixty days did not affect the formation of supragingival calculus in the present cohort of adults.