“…In contrast, the depths of the frontal and procerus muscles vary from 2 to 7 mm and from 1 to 4 mm, respectively. 5 The corrugator supercilii muscle depths are 5.3 and 4.6 mm in male and female specimens, respectively. Our drug diffusion study demonstrated that the present injection system is capable of delivering liquid from just beneath the dermis to subcutaneous tissue, including underlying mimic muscles in the face.…”