An AC biosusceptometer to study gastric emptying

Abstract

A simple AC susceptometer was developed to study the gastric emptying when test meals labeled with 10% of a harmless magnetic tracer were ingested. The instrument allows the determination of T 1/2 of the stomach emptying with good precision compared to measurements with gamma camera and 99m Tc in the test meal.

Pharyngeal Clearance and Pharyngeal Transit Time Determined by a Biomagnetic Method in Normal Humans

“…The biomagnetic method is noninvasive, causes no discomfort to the patient, does not use radiation, and has already been used to study motility functions associated with gastric emptying [11], orocecal transit time [12], gastric contractions [13], esophageal transit time [14], segmental transit time [15,16], and mixing of food in the stomach [17]. The electrical activity of the gastrointestinal tract has also been studied by measuring the magnetic ®elds produced by the depolarization currents of the stomach [18,19] and the gut [20].…”

Magnetic multiparticulate colonic delivery systems evaluated by AC Biosusceptometry

“…1B). The proximity of a magnetic material to the measurement system causes an imbalance in the magnetic flux and the response can be monitored [3,4]. The multisensor ACB system that was employed in this study, has only one pair of excitation coils (ϕ = 11.0 cm) and seven pairs of detection coils (ϕ = 2.0 cm) with 14.0 cm of baseline in a coaxial arrangement (Fig.…”

Effect of erythromycin on motility and gastric emptying in dogs, by AC Biosusceptometry

“…The aim of this work was to employ the AC Biosusceptometry (ACB) [2] technique to evaluate the Gastric Emptying Time (GET) and the Gastric Activity Contraction (GAC) in dogs after administration of erythromycin.…”