Amplification of a genomic sequence in 19th Century Human Bone DNA

Gaensslen, R. E.; Berka, Karen M.; Herrin, George; Mishler, R. E.; Sveum, L. K.; Lee, H. C.

doi:10.1007/bf01140421

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Forensic Biochemistry1

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1995

1996

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Cited by 4 publications

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“…Capillary electrophoresis was performed on PCR-amplified DNA using fluorescence detection with an intercalating dye (827). Results show that PCR amplification of a genome sequence is possible in human bones 100 years old (828). A new method for forensic identification of individuals was developed where a panel of biallelic DNA markers is amplified by PCR and the variable nucleotides are detected in the amplified DNA fragment (829).…”

Section: Forensic Biochemistrymentioning

confidence: 99%