Amperometric Nonenzymatic Determination of Glucose Free of Interference Based on Poly (Sulfosalicylic Acid) Modified Nickel Microelectrode

P1.1.11 Determination of Ltryptophan in the presence of ascorbic acid and dopamine using poly (sulfosalicylic acid) modified glassy carbon electrode

“…2 shows the typical Nyquist diagrams of the EIS in 5.0 mM [Fe(CN) 6 ] 3-/4solution at the bare GCE (a), PSA/GCE (b). Compared with the bare GCE (curve a), the electron-transfer resistance (R et ) for PSA/GCE was larger (curve b).This may be ascribed to the electrostatic repulsion force between the negatively charged [Fe(CN) 6 ] 3-/4and poly (sulfosalicylic acid) film [19]. The change of the R et value suggests that the PSA film is assembled onto the surface of GCE.…”

Technological Barriers in the Use of Electrochemical Microsensors and Microbiosensors for in vivo Analysis of Neurological Relevant Substances

“…Some membranes may provide the required selectivity for measurement in biologically relevant samples, e.g. glucose is usually detected with enzymatic microbiosensors based on glucose oxidase to take advantage of the enzymatic selectivity towards substrate, but nickel microelectrodes covered with a poly (sulfosalicylic acid) film may be used for glucose analysis with minimum interferences from ascorbic acid and uric acid [ 78 ]. All permselective membranes increase the response time due to the introduction of a diffusion layer on the sensors surface and have only limited interferences removal capacity (if the concentration of interferent is much higher than the analyte then an interfering signal is recorded).…”

Improved detection limits of toxic biochemical species based on impedance measurements in electrochemical biosensors

“…Recently, the use of microelectrodes in electrochemical detection has also been receiving close attention in this field (Li et al, 2010;Bitziou et al, in press;Raina et al, 2010;Hu et al, 2010;Lupu et al, 2010;Antohe et al, 2009;Xu et al, 2009;Kim et al, 2009;Huffman and Venton, 2009;Lee et al, 2008;Zaouak et al, 2009;Qing et al, 2008;Xiang et al, 2007). Pioneering work was done on interdigitated array (IDA) electrodes by Sanderson and Anderson (1985) and several applications were reported (Chidsey et al, 1986;Fosdick et al, 1986;Feldman and Murray, 1986;Yang, 2008;Alocilja, 2008).…”