P1.1.11 Determination of Ltryptophan in the presence of ascorbic acid and dopamine using poly (sulfosalicylic acid) modified glassy carbon electrode

Ba, Xi; Luo, Liqiang; Ding, Yaping; Liu, Xiao

doi:10.5162/imcs2012/p1.1.11

Cited by 1 publication

(2 citation statements)

References 18 publications

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“…To overcome these defects, various materials have been used to modify electrode for enhancing the selectivity and sensitivity of the electrochemical methods. 3,4 The self-assembled nanoparticles (NPs), which combined the unique physical or chemical properties of amphiphilic polymers and the hierarchical nanophase-separated nanoeffect resulted from the self-assembly of amphiphilic polymers, have been used in electrochemical sensors. 5−7 Miao et al 8 first used self-assembled botanical inositol hexakisphosphoric NPs and horseradish peroxidase via casting method to fabricate biosensor coating, which possessed a low detection limit (0.1 μmol•L −1 ) and fast response (3 s) for H 2 O 2 .…”

Section: ■ Introductionmentioning

confidence: 99%

Electrochemical Sensor Coating Based on Electrophoretic Deposition of Au-Doped Self-Assembled Nanoparticles

Zhang

Zhu

Huang

et al. 2018

ACS Appl. Mater. Interfaces

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The electrophoretic deposition (EPD) of self-assembled nanoparticles (NPs) on the surface of an electrode is a new strategy for preparing sensor coating. By simply changing the deposition conditions, the electrochemical response for an analyte of deposited NPs-based coating can be controlled. This advantage can decrease the difference between different batches of sensor coating and ensure the reproducibility of each sensor. This work investigated the effects of deposition conditions (including deposition voltage, pH value of suspension, and deposition time) on the structure and the electrochemical response for l-tryptophan of sensor coating formed from Au-doped poly(sodium γ-glutamate) with pendant dopamine units nanohybrids (Au/γ-PGA-DA NBs) via the EPD method. The structure and thickness of the deposited sensor coating were measured by atomic force microscopy, which demonstrated that the structure and thickness of coating can be affected by the deposition voltage, the pH value of the suspension, and the deposition time. The responsive current for l-tryptophan of the deposited sensor coating were measured by differential pulse voltammetry, which showed that the responsive current value was affected by the structure and thickness of the deposited coating. These arguments suggested that a rich design-space for tuning the electrochemical response for analyte and a source of variability in the structure of sensor coating can be provided by the deposition conditions. When Au/γ-PGA-DA NBs were deposited on the electrode surface and formed a continuous coating with particle morphology and thinner thickness, the deposited sensor coating exhibited optimal electrochemical response for l-tryptophan.

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Section: ■ Introductionmentioning

confidence: 99%

Electrochemical Sensor Coating Based on Electrophoretic Deposition of Au-Doped Self-Assembled Nanoparticles

Zhang

Zhu

Huang

et al. 2018

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

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“…In addition, this compound has a significant role in the mechanism of brain functions [ 8 ]. Tryptophan is commonly added to dietary food products as a food fortifier and in pharmaceutical products because of its scarce presence in vegetables and lack of ability of the body to produce it [ 9 ]. Toxic products can accumulate in the brain as a result of the improper metabolism of Trp, which can then cause problems such as hallucinations, delusions, and schizophrenia [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Delphinidin immobilized on silver nanoparticles for the simultaneous determination of ascorbic acid, noradrenalin, uric acid, and tryptophan

Nasirizadeh

Shekari

Dehghani

et al. 2016

Journal of Food and Drug Analysis

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In the present study, the fabrication of a new modified electrode for electrocatalytic oxidation of noradrenalin, based on the delphinidin immobilized on silver nanoparticles modified glassy carbon electrode. Cyclic voltammetry was used to investigate the redox properties of this modified electrode. The surface charge transfer rate constant (k) and the charge transfer coefficient (α) for the electron transfer between the glassy carbon electrode and the immobilized delphinidin were calculated. The differential pulse voltammetry exhibited two linear dynamic ranges and a detection limit of 0.40μM for noradrenalin determination. Moreover, the present electrode could separate the oxidation peak potentials of ascorbic acid, noradrenalin, uric acid, and tryptophan in a mixture. The usefulness of this nanosensor was also investigated for the determination of ascorbic acid, noradrenalin, and uric acid in pharmaceutical and biological fluid samples with satisfactory results.

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P1.1.11 Determination of Ltryptophan in the presence of ascorbic acid and dopamine using poly (sulfosalicylic acid) modified glassy carbon electrode

Cited by 1 publication

References 18 publications

Electrochemical Sensor Coating Based on Electrophoretic Deposition of Au-Doped Self-Assembled Nanoparticles

Electrochemical Sensor Coating Based on Electrophoretic Deposition of Au-Doped Self-Assembled Nanoparticles

Delphinidin immobilized on silver nanoparticles for the simultaneous determination of ascorbic acid, noradrenalin, uric acid, and tryptophan

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