Amperometric immunosensors based on layer-by-layer assembly of gold nanoparticles and methylene blue on thiourea modified glassy carbon electrode for determination of human chorionic gonadotrophin

Chai, Rong; Yuan, Ruo; Chai, Yaqin; Ou, Chaofeng; Cao, Shurui; Li, Xuelian

doi:10.1016/j.talanta.2007.08.046

Cited by 83 publications

(27 citation statements)

References 19 publications

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“…In this work, Brazil nut shells (BNS) were investigated as biosorbent to remove methylene blue (MB) and indigo carmine (IC) from aqueous solutions. MB is used in different fields, such as medicine and chemistry [24,25], and has been used as model molecule in a great number of adsorption and photocatalysis studies for environmental purposes. IC is one of the synthetic indigo dyes and is used as a colorant for food, pharmaceuticals and cosmetics [26,27].…”

Section: Introductionmentioning

confidence: 99%

Brazil nut shells as a new biosorbent to remove methylene blue and indigo carmine from aqueous solutions

Brito

Andrade

Soares

et al. 2010

Journal of Hazardous Materials

178

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Section: Introductionmentioning

confidence: 99%

Brazil nut shells as a new biosorbent to remove methylene blue and indigo carmine from aqueous solutions

Brito

Andrade

Soares

et al. 2010

Journal of Hazardous Materials

178

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“…Gold nanoparticle and methylene blue (MB) could be assembled layer-by-layer (LBL) into films on the GCE modified by thiourea for detection of human chorionic gonadotrophin (HCG) [14].Due to the high surface area of the nanoparticles for loading anti-HCG, the immunosensor would be a potential application on clinical determination of HCG level. And gold nanoparticlemodified electrode showed much wider pH adaptive range, much better electrochemical stability and larger response current to the reduction of H 2 O 2 [15].…”

Section: The Use Of Gold Nanoparticle In Biosensormentioning

confidence: 99%

Advances of Nanotechnology Applied to Biosensors

Chen¹,

Dai²,

Cui³

2011

Nano BioMed ENG

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Up to date, application of nanomaterials and nanotechnology has made great advances. Many novel nanomaterials with unique properties are increasingly being exploited to apply for biosensors, improving the property of biosensor and making them higher selectivity and sensitivity, less response time and lower detective limitation. Here we review some of the main advances in this field over the past few years, explore the application prospects, and discuss the issues, approaches, and challenges, with the amin of promting to develop nanomaterials-based biosensor nanotechnology and improving their application in disease diagnosis and biosafety examination.

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“…AuNPs have been widely used to assemble antibodies for the development of direct amperometric immunosensors [15][16][17][18][19][20][21][22][23][24][25][26][27][28][29]. In addition to the enlargement of the sensor area, these NPs show inertness, stability to chemical and physical agents, and strong adsorption ability.…”

Section: Direct Assaysmentioning

confidence: 99%

“…Other redox dyes such as thionine [15,26,27,37], prussian blue [16,28] and methylene blue [20] have been also used as electron mediators in amperometric sensors for direct tumor marker determination. One of these immunosensors for AFP determination involves the use of a composite membrane prepared by entrapping thionine in nafion, which yields an interface containing amine groups to assemble AuNPs layer for immobilization of antibodies [15].…”

Section: Direct Assaysmentioning

confidence: 99%